Evidence map›Paper›PMID 32964404›Full record

ArticleInternational journal of clinical pharmacy2021

Pharmaceutical opioids utilisation by dose, formulation, and socioeconomic status in Queensland, Australia: a population study over 22 years.

Adeleke D Adewumi, Joemer C Maravilla, Rosa Alati, Samantha A Hollingworth, Xuelei Hu, Bill Loveday, Jason P Connor

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Article in International journal of clinical pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Overview of this issue: "Pain management in an opioid crisis".International journal of clinical pharmacy · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Adeleke D AdewumiMaryborough Hospital Pharmacy, Wide Bay Hospital and Health Service, 185 Walker Street, Maryborough, QLD, 4650, Australia. a.adewumi@uqconnect.edu.au.ORCID http://orcid.org/0000-0002-6054-1242
Joemer C MaravillaInstitute for Social Science Research, The University of Queensland, 80 Meiers Rd, Indooroopilly, QLD, 4068, Australia.ORCID http://orcid.org/0000-0001-5794-9565
Rosa AlatiSchool of Public Health, Curtin University, Kent Street, Bentley Campus, Perth, WA, 6845, Australia.
Samantha A HollingworthSchool of Pharmacy, The University of Queensland, 20 Cornwall St, Woolloongabba, QLD, 4102, Australia.ORCID http://orcid.org/0000-0002-5226-5663
Xuelei HuSchool of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia.ORCID http://orcid.org/0000-0002-3759-176X
Bill LovedayMonitored Medicines Unit, Chief Medical Officer & Healthcare Regulation Branch, Department of Health, Brisbane, QLD, 4000, Australia.
Jason P ConnorDiscipline of Psychiatry, The University of Queensland, Herston, QLD, 4029, Australia.ORCID http://orcid.org/0000-0002-7020-1196
The University of Queensland · AUCurtin University · AUQueensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Prescription opioids are a central aspect of pain management and as the prevalence of pain is increasing so is the rate of use of prescription opioids. Increased opioid prescriptions increases the risk of deaths and morbidity. Objective To (a) describe the 22-year trend of prescription opioid dispensing in Queensland, (b) examine the effect of opioid dose, formulation and socioeconomic status on the number of prescriptions dispensed. Design/setting Retrospective analysis of data from the Monitoring of Drugs of Dependence system of the Monitored Medicines Unit of Queensland Health, Australia. Participants Queensland residents (3.3 million) from 18 years old dispensed 18.8 million opioid prescriptions from January 1997 to December 2018. Results Opioid prescriptions dispensed annually increased to over two million in 2018 from about 150,000 prescriptions in 1997. The number of prescriptions for modified-release formulations dispensed annually was three times higher compared to the immediate-release formulations. Oxycodone accounted for over 60% of prescriptions for pharmaceutical opioids since 2013. There was an increase in the number of prescriptions dispensed as socioeconomic status decreased and modified-release opioid formulations positively affects the pattern of dispensing. The highest increase in number of prescriptions dispensed (for all opioids) was observed among the high socioeconomic status (IRR = 1.25, 95% CI 1.25, 1.26). The disparities in the annual number of prescriptions across dose categories are wider in the modified-release than the immediate-release formulations. Conclusion The dispensing of opioids increased significantly in Queensland. There was a positive relationship between the increased dispensing of opioids and locations of lower socioeconomic status.

Indexed as

Analgesics, OpioidPharmaceutical PreparationsAustraliaDrug PrescriptionsHumansPractice Patterns, Physicians'QueenslandRetrospective StudiesSocial ClassAnalgesics, OpioidPharmaceutical PreparationsAustraliaDoseOpioidPharmaceuticalPrescriptionQueenslandSocioeconomic status

Identifiers

PMID32964404
OpenAlexW3089082910

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.