Evidence map›Paper›PMID 32964322›Full record

SynthesisJournal of gastrointestinal cancer2021

What About Gastric Schwannoma? A Review Article.

Sara Lauricella, Sergio Valeri, Gianluca Mascianà, Ida Francesca Gallo, Erica Mazzotta, Chiara Pagnoni, Saponaro Costanza, Lorenza Falcone, Domenico Benvenuto, Marco Caricato and 1 more

Registry-linked trialAbstract readComparative StudySystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07078136 (Multicenter Observational Study of a Multimodal AI Model Using EUS, White-Light Endoscopy, and Clinical Data for Diagnosis of Upper GI Mesenchymal Tumors and Risk Stratification of Gastric GISTs), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07078136 recruitingnot on this mapstarted 2025, after this paper: background citation

Multicenter Observational Study of a Multimodal AI Model Using EUS, White-Light Endoscopy, and Clinical Data for Diagnosis of Upper GI Mesenchymal Tumors and Risk Stratification of Gastric GISTs

TypeobservationalSponsorHuazhong University of Science and TechnologyRan2025 to 2026Enrolled130ConditionsSubmucosal Tumor, Gastrointestinal Stromal Tumor (GIST), Leiomyoma, SchwannomaArmsMultimodal AI Model, Expert Endoscopist Assessment
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. [Laparoscopic management of gastric schwannoma].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Schwannoma: A Rare Case of Submucosal Gastric Tumor.Diagnostics (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Article
  16. Natural history of gastrointestinal schwannomas.Endoscopy international open · 2022
    Article
  17. Review
  18. Artificial intelligence-based diagnosis of upper gastrointestinal subepithelial lesions on endoscopic ultrasonography images.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Sara LauricellaDepartment of Colorectal Surgery, Campus Bio-Medico University, Rome, Italy. s.lauricella@unicampus.it.
Sergio ValeriDepartment of Surgery for Soft Tissue Sarcoma, Campus Bio-Medico University, Rome, Italy.
Gianluca MascianàDepartment of Colorectal Surgery, Campus Bio-Medico University, Rome, Italy.
Ida Francesca GalloDepartment of Surgery for Soft Tissue Sarcoma, Campus Bio-Medico University, Rome, Italy.
Erica MazzottaDepartment of Colorectal Surgery, Campus Bio-Medico University, Rome, Italy.
Chiara PagnoniDepartment of Colorectal Surgery, Campus Bio-Medico University, Rome, Italy.
Saponaro CostanzaDepartment of Colorectal Surgery, Campus Bio-Medico University, Rome, Italy.
Lorenza FalconeDepartment of Pathology, Campus Bio-Medico University, Rome, Italy.
Domenico BenvenutoUnit of Medical Statistic and Epidemiology, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Marco CaricatoDepartment of Colorectal Surgery, Campus Bio-Medico University, Rome, Italy.
Gabriella Teresa CapolupoDepartment of Colorectal Surgery, Campus Bio-Medico University, Rome, Italy.
Università Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGastric schwannomas (GSs) are rare mesenchymal neoplasms of the gastrointestinal tract. Diagnosis is often achieved postoperatively, based on pathology reports of retrieved specimens. The aim of the present study is to follow up all patients with gastric schwannoma (Gs) undergoing endoscopic, partial, or more extended surgery and to evaluate the appearance of local or distant recurrence.

methodsA PubMed, Cochrane, and Embase systematic review of the literature has been performed. Original papers, review articles, and case reports published between 1988 and 2019 were considered eligible. All the studies who met the inclusion criteria were analyzed. Statistical analysis of data has been performed using GraphPad Prism 7 software.

resultsThree hundred twenty-eight articles were found, and a total of 102 were included and analyzed in depth. Fifty-three papers reported the follow-up information, ranging from 1 to 417 months across different studies. Among them, 31 patients underwent endoscopic removal of the gastric lesions; 140 patients underwent local surgery, including wedge resection or partial gastrectomy; and 148 patients underwent subtotal or total gastrectomy. The median follow-up was of 27-38-33 months, respectively. No recurrence or distant metastasis was detected in the endoscopy group. Among local surgery group, liver metastasis was reported in one case; in extended surgery group, one patient died for multiple liver metastases.

conclusionsLocal or more extended surgery involved a larger cohort of patients and reported satisfactory long-term results compared with endoscopy group. Surgery in absence of a definite preoperative diagnosis is considered the gold standard treatment for resectable Gs.

Indexed as

Follow-Up StudiesGastrectomyGastroscopyHumansIncidental FindingsLiver NeoplasmsNeoplasm Recurrence, LocalNeurilemmomaStomachStomach NeoplasmsTreatment OutcomeGastric neurinomaGastric schwannomaNeurinomaSchwannoma

Identifiers

PMID32964322
OpenAlexW3088157341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.