Evidence map›Paper›PMID 32964300›Full record

ArticleMagma (New York, N.Y.)2021

Variable echo time imaging for detecting the short T2* components of the sciatic nerve: a validation study.

Paolo Florent Felisaz, Eugenio Belatti, Xeni Deligianni, Niels Bergsland, Francesco Santini, Matteo Paoletti, Francesca Solazzo, Giancarlo Germani, Andrea Cortese, Elisa Vegezzi and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Magma (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 4 countries.

Paolo Florent Felisaz *Department of Neuroradiology, IRCCS Mondino Foundation, Pavia, Italy.
Eugenio Belatti *Department of Neuroradiology, IRCCS Mondino Foundation, Pavia, Italy.
Xeni DeligianniDepartment of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland. xeni.deligianni@unibas.ch.ORCID http://orcid.org/0000-0001-9968-223X
Niels BergslandDepartment of Neurology, Buffalo Neuroimaging Analysis Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Francesco SantiniDepartment of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland.
Matteo PaolettiDepartment of Neuroradiology, IRCCS Mondino Foundation, Pavia, Italy.
Francesca SolazzoDepartment of Neuroradiology, IRCCS Mondino Foundation, Pavia, Italy.
Giancarlo GermaniDepartment of Neuroradiology, IRCCS Mondino Foundation, Pavia, Italy.
Andrea CorteseDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, PV, Italy.
Elisa VegezziDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, PV, Italy.
Oliver BieriDepartment of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland.
Stefano BastianelloDepartment of Neuroradiology, IRCCS Mondino Foundation, Pavia, Italy.
Anna PichiecchioDepartment of Neuroradiology, IRCCS Mondino Foundation, Pavia, Italy.
University of Pavia · ITUniversity of Basel · CHDon Carlo Gnocchi Foundation · IT

Funding

Ministero della Salute RC 2017-2019Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 172876
6 · The paper itself

Abstract

objectiveThe aim of this study was to develop and validate an MRI protocol based on a variable echo time (vTE) sensitive to the short T2* components of the sciatic nerve. MATERIALS AND

methods15 healthy subjects (M/F: 9/6; age: 21-62) were scanned at 3T targeting the sciatic nerve at the thigh bilaterally, using a dual echo variable echo time (vTE) sequence (based on a spoiled gradient echo acquisition) with echo times of 0.98/5.37 ms. Apparent T2* (aT2*) values of the sciatic nerves were calculated with a mono-exponential fit and used for data comparison.

resultsThere were no significant differences in aT2* related to side, sex, age, and BMI, even though small differences for side were reported. Good-to-excellent repeatability and reproducibility were found for geometry of ROIs (Dice indices: intra-rater 0.68-0.7; inter-rater 0.70-0.72) and the related aT2* measures (intra-inter reader ICC 0.95-0.97; 0.66-0.85) from two different operators. Side-related signal-to-noise-ratio non-significant differences were reported, while contrast-to-noise-ratio measures were excellent both for side and echo. DISCUSSION: Our study introduces a novel MR sequence sensitive to the short T2* components of the sciatic nerve and may be used for the study of peripheral nerve disorders.

Indexed as

Magnetic Resonance ImagingSciatic NerveAdultFemaleHumansMaleMiddle AgedReproducibility of ResultsYoung AdultFibrosisMagnetic resonance imagingPeripheral nervesValidation study

Identifiers

PMID32964300
PMCPMC8154754
OpenAlexW3088777350

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.