Evidence map›Paper›PMID 32964267›Full record

ReviewCurrent cardiology reports2020

Contemporary Understandings of Cardiovascular Disease After Cancer Radiotherapy: a Focus on Ischemic Heart Disease.

Lisa Kim, Emefah C Loccoh, Reynaldo Sanchez, Patrick Ruz, Uzoma Anaba, Terence M Williams, Jeremy Slivnick, Ajay Vallakati, Ragavendra Baliga, Ahmet Ayan and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Radiation Treatment Mechanisms of Cardiotoxicity: A Systematic Review.International journal of molecular sciences · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lisa KimCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA.
Emefah C LoccohDepartment of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Reynaldo SanchezCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA.
Patrick RuzCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA.
Uzoma AnabaCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA.
Terence M WilliamsDepartment of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Jeremy SlivnickCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA.
Ajay VallakatiCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA.
Ragavendra BaligaCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA.
Ahmet AyanDepartment of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Eric D MillerDepartment of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Daniel AddisonCardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA. daniel.addison@osumc.edu.ORCID 0000-0002-9113-8333
The Ohio State University Wexner Medical Center · USThe Ohio State University · USThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Translational Training Grant in Experimental TherapeuticsK12CA133250 · NCI · OHIO STATE UNIVERSITY · PI WILLIAM E. CARSON, Rosa Lapalombella · 2008 to 2026
$15.0M
NCI NIH HHS K12 CA133250NCI NIH HHS K12CA133250NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

purpose of reviewRadiation-induced cardiovascular disease, including coronary artery disease, is a well-known sequela of radiation therapy and represents a significant source of morbidity and mortality for cancer survivors. This review examines current literature and guidelines to care for this growing population of cancer survivors. RECENT

findingsThe development of radiation-induced ischemic heart disease following radiation can lead even to early cardiotoxicities, inclusive of coronary artery disease, which limit cancer treatment outcomes. These coronary lesions tend to be diffuse, complex, and proximal. Early detection with multimodality imaging and targeted intervention is required to minimize these risks. Early awareness, detection, and management of radiation-induced cardiovascular disease are paramount as cancer survivorship continues to grow.

Indexed as

Cardiovascular DiseasesMyocardial IschemiaNeoplasmsCardiotoxicityEarly Detection of CancerHumansRadiotherapyCardiac imagingCardio-oncologyIschemic diseaseLung cancerRadiotherapyThoracic malignancies

Identifiers

PMID32964267
OpenAlexW3088883783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.