Evidence map›Paper›PMID 32963795›Full record

ArticleGlobal mental health (Cambridge, England)2020

Effectiveness of a peer-led adolescent mental health intervention on HIV virological suppression and mental health in Zimbabwe: protocol of a cluster-randomised trial.

Silindweyinkosi Chinoda, Abigail Mutsinze, Victoria Simms, Rhulani Beji-Chauke, Ruth Verhey, Joanna Robinson, Taryn Barker, Owen Mugurungi, Tsitsi Apollo, Epiphany Munetsi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Global mental health (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Silindweyinkosi ChinodaFriendship Bench, Harare, Zimbabwe.ORCID https://orcid.org/0000-0002-2384-7082
Abigail MutsinzeAfricaid, Harare, Zimbabwe.
Victoria SimmsMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Rhulani Beji-ChaukeFriendship Bench, Harare, Zimbabwe.
Ruth VerheyFriendship Bench, Harare, Zimbabwe.
Joanna RobinsonChildrens' Investment Fund Foundation, London, UK.
Taryn BarkerChildrens' Investment Fund Foundation, London, UK.
Owen MugurungiAIDS & TB Unit, Ministry of Health and Child Care, Zimbabwe.
Tsitsi ApolloAIDS & TB Unit, Ministry of Health and Child Care, Zimbabwe.
Epiphany MunetsiFriendship Bench, Harare, Zimbabwe.
Dorcas SitholeMinistry of Health and Child Care, Zimbabwe and Mental Health Services, Zimbabwe.
Helen A WeissMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Dixon ChibandaFriendship Bench, Harare, Zimbabwe.
Nicola WillisAfricaid, Harare, Zimbabwe.
Ministry of Health and Child Welfare · ZWChildren's Investment Fund Foundation · GBLondon School of Hygiene & Tropical Medicine · GBUniversity of Zimbabwe · ZW

Funding

Medical Research Council MR/R010161/1
6 · The paper itself

Abstract

backgroundAdolescents living with HIV (ALHIV) experience a high burden of mental health disorder which is a barrier to antiretroviral therapy adherence. In Zimbabwe, trained, mentored peer supporters living with HIV (Community Adolescent Treatment Supporters - CATS) have been found to improve adherence, viral suppression and psychosocial well-being among ALHIV. The Friendship Bench is the largest integrated mental health programme in Africa. We hypothesise that combining the CATS programme and Friendship Bench will improve mental health and virological suppression among ALHIV compared with the CATS programme alone.

methodsWe will conduct a cluster-randomised controlled trial in 60 clinics randomised 1:1 in five provinces. ALHIV attending the control arm clinics will receive standard CATS support and clinic support following the Ministry of Health guidelines. Those attending the intervention arm clinics will receive Friendship Bench problem-solving therapy, delivered by trained CATS. Participants with the signs of psychological distress will be referred to the clinic for further assessment and management. The primary outcome is HIV virological failure (≥1000 copies/ml) or death at 48 weeks. Secondary outcomes include the proportion of adolescents with common mental disorder symptoms (defined as Shona Symptom Questionnaire (SSQ-14) score ≥8), proportion with depression symptoms (defined as Patient Health Questionnaire (PHQ-9) score ≥11), symptom severity (mean SSQ-14 and PHQ-9 scores) and EQ-5D score for health-related quality of life.

conclusionsThis trial evaluates the effectiveness of peer-delivery of mental health care on mental health and HIV viral load among ALHIV. If effective this intervention has the potential to be scaled-up to improve these outcomes.Trial registration: PACTR201810756862405. 08 October 2018.

Indexed as

AdolescentsHIVmental health virological suppressionpeer-led

Identifiers

PMID32963795
PMCPMC7490770
OpenAlexW3082340435

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.