Evidence map›Paper›PMID 32963296›Full record

ArticleScientific reports2020

Mortality and risk of tuberculosis among people living with HIV in whom TB was initially ruled out.

Juan Ignacio García, Edson Mambuque, Dinis Nguenha, Faustino Vilanculo, Charfudin Sacoor, Victor Guillermo Sequera, Manuel Fernández-Quevedo, Maxime Leroux-La Pierre, Helio Chiconela, Luis A Faife and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Causes of death in people living with human immunodeficiency virus in Türkiye: a multicentre retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Juan Ignacio GarcíaTB Group, Population Health Program, Texas Biomedical Research Institute, San Antonio, TX, USA.ORCID https://orcid.org/0000-0001-8263-3140
Edson MambuqueCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Dinis NguenhaCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Faustino VilanculoCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Charfudin SacoorCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Victor Guillermo SequeraISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Manuel Fernández-QuevedoAgència de Salut Pública de Barcelona, Barcelona, Spain.
Maxime Leroux-La PierreISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Helio ChiconelaCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Luis A FaifeCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Durval RespeitoCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Belén SaavedraCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.ORCID https://orcid.org/0000-0002-4057-0214
Tacilta NhampossaCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Elisa López-VarelaCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.
Alberto L Garcia-BasteiroCentro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique. alberto.garcia-basteiro@manhica.net.ORCID https://orcid.org/0000-0002-2038-5505
Manhiça Health Research Centre · MZBarcelona Institute for Global Health · ESAgència de Salut Pública de Catalunya · ESDesmond Tutu HIV Foundation · ZATexas Biomedical Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) misdiagnosis remains a public health concern, especially among people living with HIV (PLHIV), given the high mortality associated with missed TB diagnoses. The main objective of this study was to describe the all-cause mortality, TB incidence rates and their associated risk factors in a cohort of PLHIV with presumptive TB in whom TB was initially ruled out. We retrospectively followed a cohort of PLHIV with presumptive TB over a 2 year-period in a rural district in Southern Mozambique. During the study period 382 PLHIV were followed-up. Mortality rate was 6.8/100 person-years (PYs) (95% CI 5.2-9.2) and TB incidence rate was 5.4/100 PYs (95% CI 3.9-7.5). Thirty-six percent of deaths and 43% of TB incident cases occurred in the first 12 months of the follow up. Mortality and TB incidence rates in the 2-year period after TB was initially ruled out was very high. The TB diagnostic work-up and linkage to HIV care should be strengthened to decrease TB burden and all-cause mortality among PLHIV with presumptive TB.

Indexed as

AdultCoinfectionFemaleHIVHIV InfectionsHumansIncidenceMaleMiddle AgedMozambiqueMycobacterium tuberculosisPrognosisRetrospective StudiesRisk FactorsSurvival RateTuberculosis

Identifiers

PMID32963296
PMCPMC7509810
OpenAlexW3088991418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.