Evidence map›Paper›PMID 32963109›Full record

ArticleRNA (New York, N.Y.)2020

NineTeen Complex-subunit Salsa is required for efficient splicing of a subset of introns and dorsal-ventral patterning.

Om Singh Rathore, Rui D Silva, Mariana Ascensão-Ferreira, Ricardo Matos, Célia Carvalho, Bruno Marques, Margarida N Tiago, Pedro Prudêncio, Raquel P Andrade, Jean-Yves Roignant and 2 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Polycomb group (PcG) proteins prevent the assembly of abnormal synaptonemal complex structures during meiosis.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Om Singh RathoreCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.
Rui D SilvaCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.ORCID 0000-0003-2168-8599
Mariana Ascensão-FerreiraInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal.
Ricardo MatosCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.
Célia CarvalhoInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal.
Bruno MarquesCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.
Margarida N TiagoCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.
Pedro PrudêncioCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.
Raquel P AndradeCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.
Jean-Yves RoignantCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0003-1395-2150
Nuno L Barbosa-MoraisInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal.ORCID 0000-0002-1215-0538
Rui Gonçalo MartinhoCenter for Biomedical Research (CBMR), Universidade do Algarve, Faro, 8005-139 Portugal.
University of Algarve · PTUniversity of Lisbon · PTAlgarve Biomedical Center · PTJohannes Gutenberg University Mainz · DE

Funding

Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
NIGMS NIH HHS R01 GM084947
6 · The paper itself

Abstract

The NineTeen Complex (NTC), also known as pre-mRNA-processing factor 19 (Prp19) complex, regulates distinct spliceosome conformational changes necessary for splicing. During

Indexed as

Gene Expression Regulation, DevelopmentalRNA SplicingAnimalsBody PatterningDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsFemaleInfertility, FemaleIntronsSpliceosomesTransforming Growth Factor alphaDNA-Binding ProteinsDrosophila Proteinsgrk protein, DrosophilaTransforming Growth Factor alphadorsal–ventral patterningDrosophilafemale fertilityGurkensplicing

Identifiers

PMID32963109
PMCPMC7668242
OpenAlexW3088504558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.