Evidence map›Paper›PMID 32963040›Full record

ArticleBMJ case reports2020

Solitary extramedullary plasmacytoma of the larynx: a rare cause of dysphonia.

Hannes Hermann Brandt, Steffi Johanna Brockmeier, Nora Tetter

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hannes Hermann BrandtDepartment of Otolaryngology, Kantonsspital Aarau AG, Aarau, Switzerland.
Steffi Johanna BrockmeierDepartment of Otolaryngology, Kantonsspital Aarau AG, Aarau, Switzerland.
Nora TetterDepartment of Otolaryngology, Kantonsspital Aarau AG, Aarau, Switzerland nora.tetter@ksa.ch.
Kantonsspital Aarau · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solitary extramedullary plasmacytoma (SEP) of the larynx is a rare haematological malignancy and an infrequent cause of persisting dysphonia. We present the case of a 54-year-old woman with a long-standing history of dysphonia. While clinical examination showed a rather inconspicuous prominent right vestibular fold, an MRI revealed a laryngeal mass with erosion of the thyroid cartilage. A biopsy taken during rigid endoscopy demonstrated plasma cell infiltration with light chain restriction amidst amyloid deposits. After exclusion of systemic involvement, the diagnosis of an SEP of the larynx with secondary amyloidosis was made. The patient received primary radiation therapy. Another biopsy taken 3 months after the end of therapy did not show any signs of ongoing neoplastic plasma cell disease. The patient was therefore considered to be in remission. She is currently receiving regular follow-up and has not shown signs of persistent or progressive disease for the past 18 months.

Indexed as

AmyloidosisBiopsyDysphoniaFemaleHumansLaryngeal NeoplasmsLaryngoscopyLarynxMagnetic Resonance ImagingMiddle AgedPlasmacytomaTreatment Outcomeear, nose and throat/otolaryngologyhaematology (incl blood transfusion)radiotherapy

Identifiers

PMID32963040
PMCPMC7509959
OpenAlexW3088363098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.