Evidence map›Paper›PMID 32963009›Full record

ArticlemBio2020

Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum.

Ranjit K Deka, Wei Z Liu, Michael V Norgard, Chad A Brautigam

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Putative mechanisms of ocular inflammation in syphilis.Journal of ophthalmic inflammation and infection · 2026
    Review
  2. The Regulatory Mechanisms of Treponema pallidum Enolase on Macrophages: From Enzymatic Activity to Signal Transduction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ranjit K DekaDepartment of Microbiology, UT Southwestern Medical Center, Dallas, Texas, USA.
Wei Z LiuDepartment of Microbiology, UT Southwestern Medical Center, Dallas, Texas, USA.
Michael V NorgardDepartment of Microbiology, UT Southwestern Medical Center, Dallas, Texas, USA.
Chad A BrautigamDepartment of Microbiology, UT Southwestern Medical Center, Dallas, Texas, USA chad.brautigam@UTSouthwestern.edu.ORCID 0000-0001-6563-1338
Southwestern Medical Center · US

Funding

The flavin-centric metabolic lifestyle of Treponema pallidumR01AI056305 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI HENDRIXSON, DAVID R · 2003 to 2024
$9.6M
NIAID NIH HHS R01 AI056305
6 · The paper itself

Abstract

A longstanding conundrum in

Indexed as

Energy MetabolismMetabolic Networks and PathwaysAcetatesAdenosine TriphosphateLactate DehydrogenasesLactic AcidPyruvic AcidTreponema pallidumAcetatesAdenosine TriphosphateD-lactate dehydrogenaseLactate DehydrogenasesLactic AcidPyruvic Acidacetogenesisd-lactate dehydrogenasespirochetesTreponema pallidumX-ray crystallography

Identifiers

PMID32963009
PMCPMC7512555
OpenAlexW3089135032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.