Evidence map›Paper›PMID 32962991›Full record

ArticleThe British journal of ophthalmology2021

Referenced scans improve the repeatability of optical coherence tomography angiography measurements in normal and glaucoma eyes.

Harsha Laxmana Rao, Srilakshmi Dasari, Mohammed Riyazuddin, Raghavan Lavanya, Narenda K P, Zia Sultan Pradhan, Sasan Moghimi, Kaweh Mansouri, Carroll A B Webers, Robert N Weinreb

Open access · greenAbstract read
In one paragraph

Article in The British journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Harsha Laxmana RaoNarayana Nethralaya, Bangalore, India harshalaxmanarao@gmail.com.ORCID 0000-0001-5866-9856
Srilakshmi DasariNarayana Nethralaya, Bangalore, India.
Mohammed RiyazuddinNarayana Nethralaya, Bangalore, India.
Raghavan LavanyaNarayana Nethralaya, Bangalore, India.
Narenda K PNarayana Nethralaya, Bangalore, India.
Zia Sultan PradhanNarayana Nethralaya, Bangalore, India.ORCID 0000-0003-4080-1665
Sasan MoghimiFarabi Eye Hospital, Tehran, Iran (the Islamic Republic of).ORCID 0000-0002-9375-4711
Kaweh MansouriHamilton Glaucoma Center, UCSD, La Jolla, California, USA.ORCID 0000-0002-7550-6749
Carroll A B WebersOphthalmology, Maastricht University, Maastricht, Netherlands.
Robert N WeinrebHamilton Glaucoma Center, Shiley Eye Institute and Department of Ophthalmology, UCSD, La Jolla, California, USA.ORCID 0000-0001-9553-3202
Narayana Nethralaya · INFarabi Hospital · IRGlaucoma Research Foundation · USMaastricht University · NL

Funding

Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography AngiographyR01EY029058 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEINREB, ROBERT N · 2018 to 2024
$4.2M
NEI NIH HHS R01 EY029058
6 · The paper itself

Abstract

aimTo compare the repeatability of peripapillary perfusion density and flux index measurements on referenced and non-referenced optical microangiography (OMAG) scans in normal, glaucoma suspect and glaucoma eyes.

methodsIn a cross-sectional study, 48 eyes (33 subjects) underwent three repeat, non-referenced peripapillary OMAG scans in the same session and 43 eyes (25 subjects) underwent three referenced peripapillary OMAG scans. In the referenced scan group, repeat scans (second and the third scan) were acquired exactly on the baseline (first) scan using the 'track to prior scan' option on the device. Repeatability estimates of the mean and four-sector (temporal, superior, nasal and inferior) OMAG measurements on the non-referenced and referenced scans were assessed using within-subject coefficient of repeatability (CR

resultsCR

conclusionsRepeatability estimates of OMAG measurements were better on referenced scans compared with non-referenced scans. Perfusion density measurements had lower variability than flux index. OCTA-measured perfusion density of referenced scans is preferable for monitoring vascular change in glaucoma.

Indexed as

GlaucomaAngiographyCross-Sectional StudiesHumansOptic DiskRetinal VesselsTomography, Optical CoherenceDiagnostic tests/InvestigationGlaucomaImaging

Identifiers

PMID32962991
PMCPMC9977392
OpenAlexW3089065481

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.