Evidence map›Paper›PMID 32962673›Full record

Trial reportBMC surgery2020

Assessment of the effect of platelet rich plasma on the healing of operated sacrococcygeal pilonidal sinus by lay-open technique: a randomized clinical trial.

Mohamed M Gohar, Reda F Ali, Khaled A Ismail, Taha A Ismail, Nahla A Nosair

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04430413 nacompletednot on this map

Assessment of the Effect of Platelet Rich Plasma on the Healing of Operated Sacrococcygeal Pilonidal Sinus by Open Method

TypeinterventionalSponsorKafrelsheikh UniversityRan2018 to 2019Enrolled100ConditionsPilonidal Disease of Natal CleftArmsPlatelet Rich Plasma
NCT06298110 phase2 / phase3unknown statusnot on this mapstarted 2024, after this paper: background citation

The Effect of PRP on Wound Healing in High Risk Patients Undergoing Abdominal Hysterectomy

TypeinterventionalSponsorHelwan UniversityRan2024 to 2024Enrolled80ConditionsWound Heal, Abdominal Wound, PRPArmsPlatelets Rich plasma of the same patient
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Platelet-rich plasma for pilonidal disease: a systematic review.The Journal of international medical research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohamed M GoharGeneral Surgery Department, Kafr El Shiekh University Hospital, Kafr El Shiekh, Egypt. dr.mmmg.1990@gmail.com.
Reda F AliGeneral Surgery Department, Kafr El Shiekh University Hospital, Kafr El Shiekh, Egypt.
Khaled A IsmailGeneral Surgery Department, Kafr El Shiekh University Hospital, Kafr El Shiekh, Egypt.
Taha A IsmailGeneral Surgery Department, Kafr El Shiekh University Hospital, Kafr El Shiekh, Egypt.
Nahla A NosairClinical Pathology Department, Kafr El Shiekh University Hospital, Kafr El Shiekh, Egypt.
Kafrelsheikh University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSacrococcygeal pilonidal sinus disease (PSD) is an infection of the skin and subcutaneous tissue at the upper part of the natal cleft of the buttocks. Excision and healing by granulation "lay-open" method is still more preferable than other methods of midline closure or using flaps but the healing time is lengthy. The present study was performed to assess the healing promotion effect of platelet-rich plasma (PRP) on the pilonidal sinus wounds treated by the lay-open method.

methodsOne hundred patients suffering from PSD were randomly divided into two groups, they were treated by the lay-open method, at General surgery department, Kafr El-Sheik University hospital, Egypt, during the period from December 2018 to December 2019. Group (A) was adopted the regular dressing postoperatively, while group (B) was treated with PRP injection into the wound at 4 and 12 postoperative days.

resultsAccelerated rate of wound healing was detected in group (B) in day 10, with a significant difference detected in days 15, 20, 25 and 30 postoperative, with a mean time of complete healing 45 ± 2.6 days in group B, while it was 57 ± 2.4 days in group A with a p-value of 0.001 which indicates considerable effect in the treated group.

conclusionsPRP injection is an effective new technique in accelerating the healing of pilonidal wound after surgery, with a significant decrease in post-operative pain, complications and an early return to work.

trial registrationretrospectively registered. TRIAL REGISTRATION NUMBER: 12/35/1016 issued on December 2018 from the Institution Review Board at Kafr El Sheikh University. ClinicalTrials.gov identifier: NCT04430413.

Indexed as

Platelet-Rich PlasmaWound HealingEgyptHumansPilonidal SinusPostoperative PainSurgical FlapsTreatment OutcomeLay-open excisionPilonidal sinusPRP

Identifiers

PMID32962673
PMCPMC7510145
OpenAlexW3089238411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.