Evidence map›Paper›PMID 32962643›Full record

ArticleBMC gastroenterology2020

The effect of prophylactic hemoclip placement and risk factors of delayed post-polypectomy bleeding in polyps sized 6 to 20 millimeters: a propensity score matching analysis.

Chun-Wei Chen, Chia-Jung Kuo, Cheng-Tang Chiu, Ming-Yao Su, Chun-Jung Lin, Puo-Hsien Le, Siew-Na Lim, Chau-Ting Yeh, Malcolm R Alison, Wey-Ran Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Chun-Wei ChenDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan.
Chia-Jung KuoDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan.
Cheng-Tang ChiuDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan.
Ming-Yao SuDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan.
Chun-Jung LinDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan.
Puo-Hsien LeDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan.
Siew-Na LimCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chau-Ting YehDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan.
Malcolm R AlisonBarts Cancer Institute, Queen Mary University of London, London, UK.
Wey-Ran LinDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, No 5, Fu Hsing Street, Guishan Dist., Taoyuan, 333, Taiwan. victor.wr.lin@gmail.com.ORCID http://orcid.org/0000-0001-6078-1396
Chang Gung University · TWLinkou Chang Gung Memorial Hospital · TWQueen Mary University of London · GB

Funding

Chang Gung Memorial Hospital, Linkou CORPG3H0151Chang Gung Memorial Hospital, Linkou CORPG3H0161Chang Gung Memorial Hospital, Linkou CORPG3H0171Chang Gung Memorial Hospital, Linkou CORPG3J0501Chang Gung Memorial Hospital, Linkou CORPG3J0521Chang Gung Memorial Hospital, Linkou CORPG3J0531
6 · The paper itself

Abstract

backgroundDelayed post-polypectomy bleeding (PPB) is a major complication of polypectomy. The effect of prophylactic hemoclipping on delayed PPB is uncertain. The aim of this study was to evaluate the effectiveness of prophylactic hemoclipping and identify the risk factors of delayed PPB.

methodsPatients with polyps sized 6 to 20 mm underwent snare polypectomy from 2015 to 2017 were retrospectively reviewed. The patients with prophylactic hemoclipping for delayed PPB prevention were included in the clipping group, and those without prophylactic hemoclipping were included in the non-clipping group. The incidence of delayed PPB and time to bleeding were compared between the groups. Multivariate analysis was used to identify the risk factors of delayed PPB. Propensity score matching was used to minimize potential bias.

resultsAfter propensity score matching, 612 patients with 806 polyps were in the clipping group, and 576 patients with 806 polyps were in the non-clipping group. There were no significant differences in the incidence of delayed PPB and days to bleeding between two groups (0.8% vs 1.3%, p = 0.4; 3.4 ± 1.94 days vs 4.13 ± 3.39 days, p = 0.94). In the multivariate analysis, the polyp size [Odds ratio (OR):1.16, 95% confidence interval (CI):1.01-1.16, p = 0.03), multiple polypectomies (OR: 4.64, 95% CI:1.24-17.44, p = 0.02) and a history of anticoagulant use (OR:37.52, 95% CI:6.49-216.8, p < 0.001) were associated with delayed PPB.

conclusionsIn polyps sized 6 to 20 mm, prophylactic hemoclip placement did not decrease the risk of delayed PPB. Patients without risk factors including multiple polypectomies and anticoagulant use are no need to performing prophylactic hemoclipping.

Indexed as

Colonic PolypsColonoscopyHumansPostoperative HemorrhagePropensity ScoreRetrospective StudiesRisk FactorsColon polypDelayed post-polypectomy bleedingHemoclipPolypectomy

Identifiers

PMID32962643
PMCPMC7510104
OpenAlexW3088790085

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.