Evidence map›Paper›PMID 32962639›Full record

ArticleBMC infectious diseases2020

Clinical characteristics of a group of deaths with COVID-19 pneumonia in Wuhan, China: a retrospective case series.

Tao Yao, Yan Gao, Qin Cui, Bo Peng, Yan Chen, Jiansheng Li, Chao Huang, Chunping He, Jie Pu, Jiajun Wei and 5 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Predictors and microbiology of respiratory and bloodstream bacterial infection in patients with COVID-19: living rapid review update and meta-regression.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Clinical manifestation, laboratory and radiology finding, treatment and outcomes of COVID-19: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tao YaoUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Yan GaoUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Qin CuiUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Bo PengUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Yan ChenUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Jiansheng LiUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Chao HuangUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Chunping HeUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Jie PuUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Jiajun WeiUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Yanqiang ZhanUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Jie YanUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Jinghua TianUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China.
Zhaohui ZhangUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China. zhangzhaohui2020@126.com.
Zhichao LiuUnion Department of Infection Disease, Wuhan University Renmin Hospital, Wuhan, 430060, China. zhichao.liu@whu.edu.cn.ORCID http://orcid.org/0000-0001-9548-7883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the widespread outbreak of novel coronavirus diseases 2019(COVID-19), more and more death cases were reported, however, limited data are available for the patients who died. We aimed to explore the clinical characteristics of deaths with COVID-19 pneumonia.

methodsWe abstracted and analyzed epidemiological, demographic, clinical, and laboratory data from 83 death cases with COVID-19 pneumonia in East Hospital of Wuhan University Renmin Hospital, between January 26, 2020, and February 28, 2020.

resultsOf the 83 deaths, none was the medical staff. The mean age was 71.8 years (SD 13.2; range, 34-97 years) and 53(63.9%) were male. The median from onset to admission was 10 days (IQR 7-14: range, 2-43 days), to death was 17 days (IQR 14-21: range, 6-54 days). Most deaths (66[80%]) had underlying comorbid diseases, the most of which was hypertension [47(57%)]. The main initial symptoms of these 83 deaths were shortness of breath(98.8%), fever(94%), and myalgia or fatigue(90.4%). Laboratory analyses showed the lymphocytopenia in 69(83%) deaths, hypoalbuminemia in 77(93%) deaths, the elevation of lactate dehydrogenase in 79(95%) deaths, procalcitonin in 69(83%) deaths and C-reactive protein in 79(95%) deaths. All 83 patients received antiviral treatment, 81(97.6%) deaths received antibiotic therapy, 54(65.1%) deaths received glucocorticoid therapy, and 20(24.1%) patients received invasive mechanical ventilation.

conclusionMost of the deaths with COVID-19 pneumonia were elderly patients with underlying comorbid diseases, especially those over 70 years of age. The time of death after the onset of the disease was mostly 15-21 days. More care should be given to the elderly in further prevention and control strategies of COVID-19.

Indexed as

AdultAgedAged, 80 and overAnti-Bacterial AgentsAntiviral AgentsBetacoronavirusChinaCoronavirus InfectionsCOVID-19C-Reactive ProteinFatigueFemaleFeverGlucocorticoidsHospitalizationHumansAnti-Bacterial AgentsAntiviral AgentsC-Reactive ProteinGlucocorticoidsL-Lactate DehydrogenaseProcalcitoninCharacteristicsCOVID-19DeathPneumonia

Identifiers

PMID32962639
PMCPMC7506806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.