Evidence map›Paper›PMID 32962638›Full record

ArticleBMC pregnancy and childbirth2020

Maternal exposure to Wenchuan earthquake and prolonged risk of offspring birth outcomes: a natural experiment study.

Qiguo Lian, Jiaying Ni, Jun Zhang, Julian Little, Shan Luo, Lin Zhang

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06110819 (Individual Training Given to Pregnant Women in the Earthquake Zone in Their Living Spaces, the Effect of Pregnancy Follow-up on Prenatal Comfort, Distress, Risk Perception and Birth Anxiety.), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06110819 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Individual Training Given to Pregnant Women in the Earthquake Zone in Their Living Spaces, the Effect of Pregnancy Follow-up on Prenatal Comfort, Distress, Risk Perception and Birth Anxiety.

TypeinterventionalSponsorTurkish Ministry of Health, Kahramanmaras Provincial Health DirectorateRan2023 to 2023Enrolled64ConditionsPregnant WomenArmscontrol, Workgroup
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. The effects of an earthquake experienced during pregnancy and perinatal outcomes.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  4. Obstetric care for environmental migrants.Irish journal of medical science · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Establishing Chinese Fetal Growth Standards: Why and How.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Qiguo LianNHC Key Lab. of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Fudan University, Shanghai, 200237, China.
Jiaying NiObstetric and Gynecology Department, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Jun ZhangMOE-Shanghai Key Lab of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Julian LittleSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, K1N 6N5, Canada.
Shan LuoWest China Second University Hospital, Sichuan University, Chengdu, 610041, China.
Lin ZhangObstetric and Gynecology Department, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. lily_yulin2003@msn.com.
Shanghai Jiao Tong University · CNFudan University · CNSichuan University · CNUniversity of Ottawa · CAXinHua Hospital · CN

Funding

Science and Technology Commission of Shanghai Municipality (CN) 201640032Shanghai Hospital Development Center SHDC12016204
6 · The paper itself

Abstract

backgroundThe prolonged effects of disasters on reproductive outcomes among the survivors are less studied, and the findings are inconsistent. We examined the associations of maternal exposure to the 2008 Wenchuan earthquake years before conception with adverse birth outcomes.

methodsWe included 73,493 women who delivered in 96 hospitals in 24 provinces and autonomous regions from the 2015/16 China Labor and Delivery Survey. We weighted the multivariable logistic models based on the combination of coarsened exact matching (CEM) weight and survey weight, and performed sex-stratified analysis to test whether associations of maternal earthquake exposure with adverse birth outcomes (Stillbirth, preterm birth [PTB], low birthweight [LBW], and small for gestational age [SGA]) varied by sex.

resultsThe bivariate models showed that the weighted incidence of each adverse birth outcome was higher in exposed group than unexposed group: stillbirth (2.00% vs. 1.33%), PTB (14.14% vs. 7.32%), LBW (10.82% vs. 5.76%), and SGA (11.32% vs. 9.52%). The multivariable models showed maternal earthquake exposure was only associated significantly with a higher risk of PTB in offspring among all births (adjusted risk ratio [aRR](95%CI):1.25(1.06-1.48), P = 0.010). The sex-stratified analysis showed the association was significant among male births (aRR (95%CI): 1.40(1.12-1.75),P = 0.002),but unsignificant among female births. The sensitivity analysis reported similar findings.

conclusionsThe 2008 Wenchuan earthquake exposure has a long-term effect on PTB. Maternal acute exposure to disasters could be a major monitor for long-term reproductive outcomes. More attention should be paid to the underlining reasons for disaster-related adverse birth outcomes.

Indexed as

EarthquakesMaternal ExposurePregnancy OutcomeAdultChinaFemaleHumansInfant, Low Birth WeightInfant, Small for Gestational AgePregnancyPremature BirthRetrospective StudiesRiskStillbirthTime FactorsYoung AdultAdverse birth outcomesPreterm birthWenchuan earthquake

Identifiers

PMID32962638
PMCPMC7510090
OpenAlexW3088071404

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.