Evidence map›Paper›PMID 32962526›Full record

ArticleJournal of the renin-angiotensin-aldosterone system : JRAAS

Influence of Angiotensin II on cell viability and apoptosis in rat renal proximal tubular epithelial cells in in vitro studies.

Aleksandra Piotrowska, Magdalena Chmielewska, Waldemar Andrzejewski, Piotr Dziegiel, Marzenna Podhorska-Okolow

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the renin-angiotensin-aldosterone system : JRAAS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Aleksandra PiotrowskaDivision of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Poland.ORCID https://orcid.org/0000-0003-4093-7386
Magdalena ChmielewskaAmphibian Biology Group, Department of Evolutionary Biology and Conservation of Vertebrates, Faculty of Biological Sciences, University of Wroclaw, Poland.ORCID https://orcid.org/0000-0002-5480-2530
Waldemar AndrzejewskiDepartment of Physiotherapy, Wroclaw University School of Physical Education, Poland.
Piotr DziegielDivision of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Poland.
Marzenna Podhorska-OkolowDivision of Ultrastructure Research, Wroclaw Medical University, Poland.
Wroclaw Medical University · PLUniversity of Wrocław · PLWroclaw University of Health and Sport Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAngiotensin II (Ang II) is multifunctional peptide that plays an important role in blood pressure regulation and maintenance electrolyte homeostasis. It shows biological effects by activating two main receptors: AT

methodsThe study was carried out using adherent NRK-52E cell line. Immunofluorescence and Western Blot method were used to confirm the presence of AT

resultsThe blockade of the AT

conclusionsThe result of our study indicates that Ang II causes damaging effect on NRK-52E cells by directing them to programmed cell death. It seems that not only does the AT

Indexed as

Angiotensin IIAnimalsApoptosisCaspase 3Cell LineCell ShapeCell SurvivalEpithelial CellsImidazolesKidney Tubules, ProximalLosartanPyridinesRatsReceptor, Angiotensin, Type 1Angiotensin IICaspase 3ImidazolesLosartanPD 123319PyridinesReceptor, Angiotensin, Type 1Ang IIAngiotensin IIapoptosisAT1AT2losartanPD123319

Identifiers

PMID32962526
PMCPMC7649907
OpenAlexW3088544627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.