Evidence map›Paper›PMID 32962487›Full record

Trial reportThe Journal of international medical research2020

Ranibizumab plus fufang xueshuantong capsule versus ranibizumab alone for exudative age-related macular degeneration.

Hai-Tao Pan, Jun-Jun Wang, Jun-Long Huang, Yuan-Lu Shuai, Jia Li, Zi-Zhong Hu, Yu-Zhi Ding, Qing-Huai Liu

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Clinical Effect of Tongmai Fuming Decoction on Neovascular Ophthalmopathy.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  7. Clinical Efficacy of Xueshuantong plus Urokinase in the Treatment of Sudden Deafness.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hai-Tao PanDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0001-8941-3810
Jun-Jun WangDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jun-Long HuangDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yuan-Lu ShuaiDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jia LiDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zi-Zhong HuDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yu-Zhi DingDepartment of Ophthalmology, Zhongda Hospital Southeast University, Nanjing, China.
Qing-Huai LiuDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNNanjing General Hospital of Nanjing Military Command · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the efficacy of ranibizumab plus fufang xueshuantong capsule (cFXST) with the efficacy of ranibizumab alone in treatment of exudative age-related macular degeneration.

methodsThis prospective, randomized, controlled, pilot study included 38 eyes from 38 patients with exudative age-related macular degeneration (AMD) that were randomly allocated into two cohorts of 19 eyes each: ranibizumab (C

resultsIn the C

conclusionOral cFXST increases the efficacy of short-term ranibizumab treatment for exudative AMD.

Indexed as

Macular DegenerationRanibizumabAngiogenesis InhibitorsDrugs, Chinese HerbalHumansIntravitreal InjectionsPilot ProjectsProspective StudiesTomography, Optical CoherenceTreatment OutcomeVisual AcuityAngiogenesis InhibitorsDrugs, Chinese HerbalPanax notoginseng extractRanibizumabage-related macular degenerationchoroidal neovascularizationcombination therapyFufang xueshuantongranibizumabtraditional Chinese medicine

Identifiers

PMID32962487
PMCPMC7520929
OpenAlexW3088924223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.