Evidence map›Paper›PMID 32962483›Full record

ArticlePharmaceutical biology2020

Preliminary study of Yinhuapinggan granule against H1N1 influenza virus infection in mice through inhibition of apoptosis.

Hai-Xia Du, Hui-Fen Zhou, Jie-Hong Yang, Yi-Yu Lu, Yu He, Hai-Tong Wan

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Inhibitory Effects and Related Molecular Mechanisms of Huanglian-Ganjiang Combination Against H1N1 Influenza Virus.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2023
    Article
  6. Article
  7. Anti-Influenza Effect and Mechanisms of Lentinan in an ICR Mouse Model.Frontiers in cellular and infection microbiology · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hai-Xia DuCollege of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China.ORCID https://orcid.org/0000-0002-6566-1577
Hui-Fen ZhouCollege of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Jie-Hong YangCollege of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Yi-Yu LuInstitute of Microbiology, Zhejiang Center for Disease Control and Prevention, Hangzhou, China.
Yu HeCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.ORCID https://orcid.org/0000-0002-5802-051X
Hai-Tong WanCollege of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Zhejiang Chinese Medical University · CNZhejiang Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextYinhuapinggan granule (YHPG) is frequently used for treating fever, cough, and viral pneumonia in traditional Chinese medicine.

objectiveThis study investigated the antiviral effects of YHPG in H1N1 influenza virus (IFV)-infected mice and its possible mechanism. MATERIALS AND

methodsICR mice were intranasally infected with 10 LD

resultsLD

conclusionsYHPG has significant antiviral effects in IFV-infected mice, partially by inhibiting influenza virus replication and regulating the occurrence of apoptosis induced by influenza virus infection, suggesting that YHPG may be a promising antiviral agent with potential clinical application prospects.

Indexed as

AnimalsAntiviral AgentsApoptosisDisease Models, AnimalDrugs, Chinese HerbalInfluenza A Virus, H1N1 SubtypeMaleMedicine, Chinese TraditionalMiceMice, Inbred ICROrthomyxoviridae InfectionsViral LoadVirus ReplicationAntiviral AgentsDrugs, Chinese Herbalyinhuapingganapoptosis signalling pathwayTraditional Chinese medicine

Identifiers

PMID32962483
PMCPMC7534346
OpenAlexW3089329648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.