Evidence map›Paper›PMID 32962278›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Association between Polygenic Risk Score and One-Year Outcomes Following As-Needed Aflibercept Therapy for Exudative Age-Related Macular Degeneration.

Taiyo Shijo, Yoichi Sakurada, Seigo Yoneyama, Wataru Kikushima, Atsushi Sugiyama, Mio Matsubara, Yoshiko Fukuda, Fumihiko Mabuchi, Kenji Kashiwagi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Taiyo ShijoDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Yoichi SakuradaDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Seigo YoneyamaDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Wataru KikushimaDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Atsushi SugiyamaDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Mio MatsubaraDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Yoshiko FukudaDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Fumihiko MabuchiDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Kenji KashiwagiDepartment of Ophthalmology, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.ORCID 0000-0001-8506-8503
University of Yamanashi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether polygenic risk score (PRS) was associated with one-year outcome of as-needed aflibercept therapy for exudative age-related macular degeneration (AMD), including AMD (

Indexed as

aflibercept therapyage-related macular degenerationARMS2CFHpolygenic risk scoretreatment outcomes

Identifiers

PMID32962278
PMCPMC7559528
OpenAlexW3087470814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.