Evidence map›Paper›PMID 32962203›Full record

ArticleViruses2020

PA from a Recent H9N2 (G1-Like) Avian Influenza a Virus (AIV) Strain Carrying Lysine 367 Confers Altered Replication Efficiency and Pathogenicity to Contemporaneous H5N1 in Mammalian Systems.

Ahmed Mostafa, Sara H Mahmoud, Mahmoud Shehata, Christin Müller, Ahmed Kandeil, Rabeh El-Shesheny, Hanaa Z Nooh, Ghazi Kayali, Mohamed A Ali, Stephan Pleschka

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  9. PhytoestrogenVaccines · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Ahmed MostafaCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), 12622 Giza, Egypt.ORCID 0000-0002-2878-5714
Sara H MahmoudCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), 12622 Giza, Egypt.
Mahmoud ShehataCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), 12622 Giza, Egypt.ORCID 0000-0001-7556-9398
Christin MüllerInstitute of Medical Virology, Justus Liebig University Giessen, Schubertstrasse 81, 35390 Giessen, Germany.ORCID 0000-0002-6444-9478
Ahmed KandeilCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), 12622 Giza, Egypt.ORCID 0000-0003-3253-6961
Rabeh El-SheshenyCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), 12622 Giza, Egypt.ORCID 0000-0002-8798-2240
Hanaa Z NoohAnatomy and Embryology Department, Faculty of Medicine, Jouf University, Sakaka 2014, Saudi Arabia.ORCID 0000-0001-9464-4971
Ghazi KayaliDepartment of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas, Houston, TX 77030, USA.
Mohamed A AliCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), 12622 Giza, Egypt.ORCID 0000-0002-5615-3212
Stephan PleschkaInstitute of Medical Virology, Justus Liebig University Giessen, Schubertstrasse 81, 35390 Giessen, Germany.
National Research Centre · EGJustus-Liebig-Universität Gießen · DEJouf University · SASt. Jude Children's Research Hospital · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Egypt is a hotspot for H5- and H9-subtype avian influenza A virus (AIV) infections and co-infections in poultry by both subtypes have been frequently reported. However, natural genetic reassortment of these subtypes has not been reported yet. Here, we evaluated the genetic compatibility and replication efficiency of reassortants between recent isolates of an Egyptian H5N1 and a H9N2 AIV (H5N1

Indexed as

A549 CellsAnimalsDogsEgyptFemaleHumansInfluenza A Virus, H5N1 SubtypeInfluenza A Virus, H9N2 SubtypeInfluenza in BirdsLysineMadin Darby Canine Kidney CellsMammalsMiceMice, Inbred BALB COrthomyxoviridae InfectionsPoultryLysineViral Proteinsavian influenzaH5N1H9N2pathogenicityR367Kreassortment

Identifiers

PMID32962203
PMCPMC7551781
OpenAlexW3087255345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.