Evidence map›Paper›PMID 32962193›Full record

ArticleToxins2020

Antibiofilm Activity of Acidic Phospholipase Isoform Isolated from

Ellynes Nunes, Breno Frihling, Elizângela Barros, Caio de Oliveira, Newton Verbisck, Taylla Flores, Augusto de Freitas Júnior, Octávio Franco, Maria de Macedo, Ludovico Migliolo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Antimicrobial Resistance: The Answers.British journal of biomedical science · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Inhibition of bacterial biofilms by the snake venom proteome.Biotechnology reports (Amsterdam, Netherlands) · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Ellynes NunesPostgraduate Program in Cellular and Molecular Biology-Federal University of Paraíba, João Pessoa, PB 58051-900, Brazil.
Breno FrihlingS-Inova Biotech, Postgraduate Program in Biotechnology-Dom Bosco Catholic University, Campo Grande, MS 79117-010, Brazil.ORCID 0000-0002-3749-9410
Elizângela BarrosS-Inova Biotech, Postgraduate Program in Biotechnology-Dom Bosco Catholic University, Campo Grande, MS 79117-010, Brazil.
Caio de OliveiraProtein Purification Laboratory and its Biological Functions, Faculty of Medicine, FAMED, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS 79603-011, Brazil.ORCID 0000-0001-9549-4848
Newton VerbisckEmbrapa Beef Cattle, Campo Grande, MS 79106-550, Brazil.ORCID 0000-0001-9817-7223
Taylla FloresPostgraduate Program in Cellular and Molecular Biology-Federal University of Paraíba, João Pessoa, PB 58051-900, Brazil.
Augusto de Freitas JúniorPostgraduate Program in Cellular and Molecular Biology-Federal University of Paraíba, João Pessoa, PB 58051-900, Brazil.
Octávio FrancoS-Inova Biotech, Postgraduate Program in Biotechnology-Dom Bosco Catholic University, Campo Grande, MS 79117-010, Brazil.ORCID 0000-0001-9546-0525
Maria de MacedoProtein Purification Laboratory and its Biological Functions, Faculty of Medicine, FAMED, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS 79603-011, Brazil.ORCID 0000-0001-6969-6307
Ludovico MiglioloPostgraduate Program in Cellular and Molecular Biology-Federal University of Paraíba, João Pessoa, PB 58051-900, Brazil.ORCID 0000-0002-6606-2189
Karla LunaPostgraduate Program in Cellular and Molecular Biology-Federal University of Paraíba, João Pessoa, PB 58051-900, Brazil.
Universidade Federal da Paraíba · BRBiotech (Brazil) · BRUniversidade Federal de Mato Grosso do Sul · BRBrazilian Agricultural Research Corporation · BRUniversidade Católica de Brasília · BRUniversidade Estadual da Paraíba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBacterial resistance is a worldwide public health problem, requiring new therapeutic options. An alternative approach to this problem is the use of animal toxins isolated from snake venom, such as phospholipases A

methodsVenom extraction and quantification were followed by reverse-phase high-performance liquid chromatography (RP-HPLC) in C18 column, matrix-assisted ionization time-of-flight (MALDI-ToF) mass spectrometry, and sequencing by Edman degradation. All experiments were monitored by specific activity using a 4-nitro-3-(octanoyloxy) benzoic acid (4N

resultsPLA

conclusionsThis is the first time that PLA

Indexed as

Acinetobacter baumanniiAnimalsAnti-Bacterial AgentsBiofilmsBothropsCrotalid VenomsEscherichia coliPhospholipases A2Reptilian ProteinsStaphylococcus aureusAnti-Bacterial AgentsCrotalid VenomsPhospholipases A2Reptilian Proteinsanimal venomantibacterial and antibiofilm activitybacterial resistancepurification

Identifiers

PMID32962193
PMCPMC7551604
OpenAlexW3042032753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.