Evidence map›Paper›PMID 32962127›Full record

ArticleMolecules (Basel, Switzerland)2020

Synthesis and Evaluation of the Antitumor Activity of Novel 1-(4-Substituted phenyl)-2-ethyl Imidazole Apoptosis Inducers In Vitro.

Zhen-Wang Li, Chun-Yan Zhong, Xiao-Ran Wang, Shi-Nian Li, Chun-Yuan Pan, Xin Wang, Xian-Yu Sun

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhen-Wang LiCollege of Animal Science and Technique, Heilongjiang Bayi Agriculture University, Daqing 163319, Heilongjiang, China.
Chun-Yan ZhongCollege of Animal Science and Technique, Heilongjiang Bayi Agriculture University, Daqing 163319, Heilongjiang, China.
Xiao-Ran WangCollege of Animal Science and Technique, Heilongjiang Bayi Agriculture University, Daqing 163319, Heilongjiang, China.
Shi-Nian LiCollege of Animal Science and Technique, Heilongjiang Bayi Agriculture University, Daqing 163319, Heilongjiang, China.
Chun-Yuan PanCollege of Animal Science and Technique, Heilongjiang Bayi Agriculture University, Daqing 163319, Heilongjiang, China.
Xin WangCollege of Animal Science and Technique, Heilongjiang Bayi Agriculture University, Daqing 163319, Heilongjiang, China.
Xian-Yu SunCollege of Animal Science and Technique, Heilongjiang Bayi Agriculture University, Daqing 163319, Heilongjiang, China.

Funding

Heilongjiang Bayi Agricultural University Graduate Students Innovation Project [YJSCX2019-Y34]National Natural Science Foundation of China [Grant No. 81502922]Program for Young Scholars with Creative Talents in HeiLongJiang BaYi Agricultural University [CXRC2016-9]
6 · The paper itself

Abstract

Novel imidazole derivatives were designed, prepared, and evaluated in vitro for antitumor activity. The majority of the tested derivatives showed improved antiproliferative activity compared to the positive control drugs 5-FU and MTX. Among them, compound

Indexed as

Antineoplastic AgentsApoptosisCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorFluorouracilHumansImidazolesStructure-Activity RelationshipAntineoplastic AgentsFluorouracilImidazolesantitumorapoptosisBaxBcl-2imidazole

Identifiers

PMID32962127
PMCPMC7570620

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.