Evidence map›Paper›PMID 32961942›Full record

ArticlePharmaceutics2020

Imaging of the Effect of Alcohol-Containing Media on the Performance of Hypromellose Hydrophilic Matrix Tablets: Comparison of Direct Compression and Regular Grades of Polymer.

Nihad Mawla, Sarah Hanley, Karl Walton, Waseem Kaialy, Tariq Hussain, Adam Ward, Jonathan Brown, Barbara R Conway, Peter Timmins, Kofi Asare-Addo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Nihad MawlaDepartment of Pharmacy, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Sarah HanleyDrug Product Science and Technology, Bristol Myers Squibb, Moreton, Merseyside CH46 1QW, UK.
Karl WaltonEPSRC Future Metrology Hub, University of Huddersfield, Huddersfield HD1 3DH, UK.
Waseem KaialySchool of Pharmacy, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton WV1 1LY, UK.
Tariq HussainThe Wolfson Centre for Bulk Solids Handling Technology, Medway School of Engineering, University of Greenwich, Kent ME4 4TB, UK.
Adam WardDepartment of Pharmacy, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Jonathan BrownDrug Product Science and Technology, Bristol Myers Squibb, Moreton, Merseyside CH46 1QW, UK.
Barbara R ConwayDepartment of Pharmacy, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.ORCID 0000-0001-5570-3318
Peter TimminsDepartment of Pharmacy, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.ORCID 0000-0002-5840-0678
Kofi Asare-AddoDepartment of Pharmacy, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
University of Huddersfield · GBBristol-Myers Squibb (United Kingdom) · GBEngineering and Physical Sciences Research Council · GBUniversity of Greenwich · GBUniversity of Wolverhampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the ingestion of drug products with alcohol could have adverse effects on the release of drugs from dosage forms, it is important to understand the mechanisms underpinning the influence on drug release by evaluating the effect of alcohol-containing media on the behaviour of pharmaceutical excipients. In this work, the effect of hydroalcoholic media containing up to 40%

Indexed as

alcoholdissolutionhypromellosemagnetic resonance imagingtomographytribo-electrification

Identifiers

PMID32961942
PMCPMC7559722
OpenAlexW3087298250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.