Evidence map›Paper›PMID 32961801›Full record

Trial reportInternational journal of molecular sciences2020

Circulating Vitamin D Levels and DNA Repair Capacity in Four Molecular Subtypes of Women with Breast Cancer.

Carmen Ortiz-Sánchez, Jarline Encarnación-Medina, Ralphdy Vergne, Luis Padilla, Jaime Matta

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Carmen Ortiz-SánchezDepartment of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University-School of Medicine, Ponce, PR 00716, USA.ORCID 0000-0003-3567-7866
Jarline Encarnación-MedinaDepartment of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University-School of Medicine, Ponce, PR 00716, USA.ORCID 0000-0002-0354-6274
Ralphdy VergneBiomedical Sciences Department, Interamerican University of Puerto Rico, Ponce, PR 00715, USA.
Luis PadillaBiology Department, University of Puerto Rico at Ponce, Ponce, PR 00716, USA.
Jaime MattaDepartment of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University-School of Medicine, Ponce, PR 00716, USA.ORCID 0000-0001-6668-9021
Ponce Health Sciences University · PRInterAmerican University of Puerto Rico · PRUniversity of Puerto Rico at Ponce · PR

Funding

Using MC1R genotype to impact skin cancer risk behaviors in Hispanics/LatinosU54CA163068 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Shannon Marie Christy · 2012 to 2026
$23.1M
Using MC1R genotype to impact skin cancer risk behaviors in Hispanics/LatinosU54CA163071 · NCI · PONCE SCHOOL OF MEDICINE · PI Harold I Saavedra · 2012 to 2026
$23.0M
UNIVERSITY OF PUERTO RICO PONCE RESEARCH INITIATIVE FOR SCIENTIFIC ENHANCEMENT: UR25GM096955 · NIGMS · UNIVERSITY OF PUERTO RICO PONCE · PI SUAREZ-MARTINEZ, EDU B · 2011 to 2020
$5.7M
NCI NIH HHS 5U54CA163071-04NCI NIH HHS U54 CA163068NCI NIH HHS U54 CA163071NIGMS NIH HHS 5R25GM096955-08NIGMS NIH HHS R25 GM096955NIH HHS 5SC1CA157250-02NIH HHS 9SC1CA182846-04NIH HHS S06GM008239-20
6 · The paper itself

Abstract

Vitamin D regulates estrogen synthesis among other mechanisms involved in breast cancer (BC) development; however, no evidence has been found regarding its relationship with DNA repair capacity (DRC). Therefore, the objective of this study was to elucidate whether DRC levels are linked with plasma 25(OH)D levels. BC cases and controls were selected from our BC cohort. DRC levels were assessed in lymphocytes through the host-cell reactivation assay. 25(OH)D levels were measured using the UniCel DxI 600 Access Immunoassay System. BC cases (

Indexed as

Breast NeoplasmsDNA RepairAdultAgedDNA, NeoplasmFemaleHumansLymphocytesMiddle AgedVitamin D25-hydroxyvitamin DDNA, NeoplasmVitamin Dbreast cancerDNA repair capacityhost-cell reaction assaymolecular subtypesnucleotide excision repairplasma 25-hydroxyvitamin D (25(OH)D)vitamin D

Identifiers

PMID32961801
PMCPMC7555346
OpenAlexW3087183646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.