Evidence map›Paper›PMID 32961799›Full record

ArticleSensors (Basel, Switzerland)2020

Turning Detection During Gait: Algorithm Validation and Influence of Sensor Location and Turning Characteristics in the Classification of Parkinson's Disease.

Rana Zia Ur Rehman, Philipp Klocke, Sofia Hryniv, Brook Galna, Lynn Rochester, Silvia Del Din, Lisa Alcock

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rana Zia Ur RehmanTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Philipp KlockeClinical Ageing Research Unit, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.ORCID 0000-0003-0868-5270
Sofia HrynivClinical Ageing Research Unit, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.ORCID 0000-0002-5860-7986
Brook GalnaTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Lynn RochesterTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Silvia Del DinTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.ORCID 0000-0003-1154-4751
Lisa AlcockTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Newcastle Hospitals - Campus for Ageing and Vitality · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBUniversity of Cambridge · GB

Funding

Parkinson's UK G-1301Parkinson's UK J-0802Parkinson's UK J-0802, G-1301
6 · The paper itself

Abstract

Parkinson's disease (PD) is a common neurodegenerative disorder resulting in a range of mobility deficits affecting gait, balance and turning. In this paper, we present: (i) the development and validation of an algorithm to detect turns during gait; (ii) a method to extract turn characteristics; and (iii) the classification of PD using turn characteristics. Thirty-seven people with PD and 56 controls performed 180-degree turns during an intermittent walking task. Inertial measurement units were attached to the head, neck, lower back and ankles. A turning detection algorithm was developed and validated by two raters using video data. Spatiotemporal and signal-based characteristics were extracted and used for PD classification. There was excellent absolute agreement between the rater and the algorithm for identifying turn start and end (ICC ≥ 0.99). Classification modeling (partial least square discriminant analysis (PLS-DA)) gave the best accuracy of 97.85% when trained on upper body and ankle data. Balanced sensitivity (97%) and specificity (96.43%) were achieved using turning characteristics from the neck, lower back and ankles. Turning characteristics, in particular angular velocity, duration, number of steps, jerk and root mean square distinguished mild-moderate PD from controls accurately and warrant future examination as a marker of mobility impairment and fall risk in PD.

Indexed as

Gait AnalysisGait Disorders, NeurologicParkinson DiseaseAgedAlgorithmsFemaleHumansMaleMiddle AgedWalkinginertial measurement unit (IMU)lower bodymachine learningPLS-DAsignal-based characteristicsspatial-temporal characteristicsupper bodyvalidationwearables

Identifiers

PMID32961799
PMCPMC7570702
OpenAlexW3087200254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.