Evidence map›Paper›PMID 32961767›Full record

ArticleCells2020

Juniperonic Acid Biosynthesis is Essential in

Sujay Guha, Serafina Calarco, M Salomé Gachet, Jürg Gertsch

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sujay GuhaInstitute of Biochemistry and Molecular Medicine, NCCR TransCure, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Serafina CalarcoInstitute of Biochemistry and Molecular Medicine, NCCR TransCure, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.ORCID 0000-0002-5330-5516
M Salomé GachetInstitute of Biochemistry and Molecular Medicine, NCCR TransCure, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Jürg GertschInstitute of Biochemistry and Molecular Medicine, NCCR TransCure, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
University of Bern · CH

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

In eukaryotes, the C20:4 polyunsaturated fatty acid arachidonic acid (AA) plays important roles as a phospholipid component, signaling molecule and precursor of the endocannabinoid-prostanoid axis. Accordingly, the absence of AA causes detrimental effects. Here, compensatory mechanisms involved in AA deficiency in

Indexed as

AcetyltransferasesAnimalsArachidonic AcidCadherinsCaenorhabditis elegansCaenorhabditis elegans ProteinsDelta-5 Fatty Acid DesaturaseEndocannabinoidsEpidermal Growth FactorFatty Acid DesaturasesFatty Acids, UnsaturatedGene Expression RegulationLinoleic AcidLongevityMutationReceptors, G-Protein-CoupledAcetyltransferasesArachidonic AcidCadherinsCaenorhabditis elegans ProteinsDelta-5 Fatty Acid DesaturaseEndocannabinoidsEpidermal Growth Factorfat-3 protein, C elegansFatty Acid DesaturasesFatty Acids, Unsaturatedjuniperonic acidLinoleic AcidNPR-32 protein, C elegansReceptors, G-Protein-Coupledarachidonic acid (AA)biosynthesisC20:4 polyunsaturated fatty acidC. elegansendocannabinoidsjuniperonic acid (JuA)

Identifiers

PMID32961767
PMCPMC7564282
OpenAlexW3087639270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.