Evidence map›Paper›PMID 32961695›Full record

ArticleNutrients2020

High Dose Intravenous Fish Oil Reduces Inflammation-A Retrospective Tale from Two Centers.

Stanislaw Klek, Dorota Mankowska-Wierzbicka, Lucyna Scislo, Elzbieta Walewska, Magdalena Pietka, Kinga Szczepanek

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Stanislaw KlekGeneral Surgery Unit, Stanley Dudrick's Memorial Hospital, 15 Tyniecka Street, 32-050 Skawina, Poland.
Dorota Mankowska-WierzbickaDepartment of Gastroenterology, Metabolic Diseases, Internal Medicine and Dietetics, Poznan University of Medical Sciences, 60-001 Poznan, Poland.ORCID 0000-0003-2577-5905
Lucyna ScisloDepartment of Clinical Nursing, Institute of Nursing and Midwifery, Faculty of Health Care, Jagiellonian University, 30-130 Krakow, Poland.
Elzbieta WalewskaDepartment of Clinical Nursing, Institute of Nursing and Midwifery, Faculty of Health Care, Jagiellonian University, 30-130 Krakow, Poland.
Magdalena PietkaGeneral Surgery Unit, Stanley Dudrick's Memorial Hospital, 15 Tyniecka Street, 32-050 Skawina, Poland.
Kinga SzczepanekGeneral Surgery Unit, Stanley Dudrick's Memorial Hospital, 15 Tyniecka Street, 32-050 Skawina, Poland.
Jagiellonian University · PLPoznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimPatients on parenteral nutrition (PN) are prone to inflammation. This may aggravate an existing proinflammatory state and become a critical factor in the development of liver dysfunction (LD). Intravenous fish oil may attenuate this inflammatory state, but data on its use in adults are scarce. The aim of this study was to investigate the effects of adding a pure fish oil intravenous lipid emulsion (ILE) into short- and long-term PN in patients either at risk of, or with existing, inflammation.

methodsA retrospective analysis of 61 patients (32 female, 29 male, mean age 51.5 ± 12.6 years) who received all-in-one PN, including amino acids, glucose, and lipids supplemented with pure fish oil ILE, was performed. Pure fish oil ILE (Omegaven®, Fresenius Kabi, Bad Homburg, Germany) was used along with the standard ILE to reach a fish oil dose of 0.4-0.5 g fish oil/kg/d. Diagnoses were chronic intestinal failure (CIF,

resultsA reduction in inflammation was noticeable in all patients and became statistically significant in CD (hsCRP

conclusionsPN with pure fish oil ILE reduces some inflammatory parameters in IBD and maintains liver function parameters in CIF patients. Fish oil might become a valuable ingredient in both short- and long-term PN in patients at risk of liver dysfunction.

Indexed as

Parenteral NutritionAdultFemaleFish OilsHumansInflammationMaleMiddle AgedPolandRetrospective StudiesFish Oilsfish oillipid emulsionsomega-3 fatty acidsomega-3 PUFAparenteral nutrition

Identifiers

PMID32961695
PMCPMC7551918
OpenAlexW3087012049

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.