Evidence map›Paper›PMID 32961661›Full record

Trial reportInternational journal of molecular sciences2020

Elevated Pro-Inflammatory Cell-Free MicroRNA Levels in Cerebrospinal Fluid of Premature Infants after Intraventricular Hemorrhage.

Zsolt Fejes, Judit Erdei, Marianna Pócsi, Jun Takai, Viktória Jeney, Andrea Nagy, Alíz Varga, Attila Bácsi, László Bognár, László Novák and 2 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Inflammatory hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Zsolt FejesDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-1387-2970
Judit ErdeiMTA-DE Lendület Vascular Pathophysiology Research Group, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-1652-4506
Marianna PócsiDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Jun TakaiDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Viktória JeneyMTA-DE Lendület Vascular Pathophysiology Research Group, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-4942-7091
Andrea NagyDepartment of Pediatrics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Alíz VargaDepartment of Immunology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Attila BácsiDepartment of Immunology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
László BognárDepartment of Neurosurgery, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
László NovákDepartment of Neurosurgery, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
János KappelmayerDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Béla NagyDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraventricular hemorrhage (IVH) represents a high risk of neonatal mortality and later neurodevelopmental impairment in prematurity. IVH is accompanied with inflammation, hemolysis, and extracellular hemoglobin (Hb) oxidation. However, microRNA (miRNA) expression in cerebrospinal fluid (CSF) of preterm infants with IVH has been unknown. Therefore, in the present study, candidate pro-inflammatory cell-free miRNAs were analyzed in CSF samples from 47 preterm infants with grade III or IV IVH vs. clinical controls (

Indexed as

BiomarkersCell LineCerebral HemorrhageCirculating MicroRNAFemaleHumansInfantInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureMaleBiomarkersCirculating MicroRNAcerebrospinal fluidhemeinflammationintraventricular hemorrhagemicroRNAoxidized hemoglobin

Identifiers

PMID32961661
PMCPMC7557369
OpenAlexW3087017125

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.