Evidence map›Paper›PMID 32961294›Full record

ArticleFish & shellfish immunology2020

Transient increase in abundance of B lineage but not myeloid-lineage cells in anterior kidney of sockeye salmon during return migration to the natal grounds.

Meaghan K Smith, Patty Zwollo

Open access · greenAbstract read
In one paragraph

Article in Fish & shellfish immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Meaghan K SmithDepartment of Biology, The College of William and Mary, Williamsburg, VA, 23185, USA.
Patty ZwolloDepartment of Biology, The College of William and Mary, Williamsburg, VA, 23185, USA. Electronic address: pxzwol@wm.edu.
Williams (United States) · US

Funding

Role of immune progenitors in regulation of genetic resistance against bacterial pathogensR15AI119978 · NIAID · COLLEGE OF WILLIAM AND MARY · PI ZWOLLO, PATTY · 2015 to 2015
$364k
NIAID NIH HHS R15 AI119978
6 · The paper itself

Abstract

As anadromous fish, sockeye salmon undergo complex endocrine changes when they return to their natal grounds to spawn. This is correlated with major immunological changes that will affect their response to pathogens. In spite of these challenges, salmon need to maintain sufficiently robust immunity to survive until spawning is complete, but the nature of immune adaptations during the spawning stage remains poorly understood. Our central question is to determine if sockeye salmon stimulate their immune system during the return migration and if so, whether this is a protective response. To begin answering this question, here we characterized the nature and timing of potential changes in anterior kidney immune fingerprints between salmon collected from seven different sites along the Kenai river, including the mouth of the river and two spawning sites. Our results revealed significant changes in abundance of B lineage, but not myeloid lineage cells during the spawning journey. This included early, transient and significant increases in abundance of both IgM

Indexed as

Cell LineageAlaskaAnimal MigrationAnimalsB-LymphocytesFemaleHead KidneyMaleMyeloid CellsSalmon

Identifiers

PMID32961294
PMCPMC7718325
OpenAlexW3087225908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.