Evidence map›Paper›PMID 32961225›Full record

ArticleUrology2021

Statewide Price Variation for Generic Benign Prostatic Hyperplasia Medications.

Anup A Shah, Praveen Kumar, Ayodele G Ogunmola, Omar Ayyash, Jonathan G Yabes, Lindsay M Sabik, Anobel Y Odisho, Jathin Bandari, Liam C Macleod, Benjamin J Davies and 1 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Anup A ShahDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: shahaa2@upmc.edu.
Praveen KumarDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. Electronic address: prk52@pitt.edu.
Ayodele G OgunmolaUniversity of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: ogunmola.ayodele@medstudent.pitt.edu.
Omar AyyashDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: ayyasho@upmc.edu.
Jonathan G YabesDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. Electronic address: jgy2@pitt.edu.
Lindsay M SabikDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. Electronic address: lsabik@pitt.edu.
Anobel Y OdishoDepartment of Urology, School of Medicine, University of California, San Francisco, CA. Electronic address: anobel.odisho@ucsf.edu.
Jathin BandariDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: bandarij@upmc.edu.
Liam C MacleodDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: liamcmacleod@gmail.com.
Benjamin J DaviesDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: daviesbj@upmc.edu.
Bruce L JacobsDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: jacobsbl2@upmc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the geographic and pharmacy-type variation in costs for generic benign prostatic hyperplasia (BPH) medications in order to improve drug price transparency and reduce health disparities. Medical therapy for BPH can be expensive, having significant implications for uninsured and underinsured patients.

methodsWe generated a 20% random sample of all pharmacies in Pennsylvania and queried each for the uninsured cash price of a 30-day prescription of tamsulosin 0.4mg daily, finasteride 5mg daily, oxybutynin immediate release 5mg TID and oxybutynin XL 10mg daily. Our primary objectives were to identify price variation based on pharmacy type (i.e., big chain and independent) and between geographic regions (predetermined by the Pennsylvania Health Care Cost Containment Council Database). We fit multivariable quantile regression models to test for an association between drug price and region after controlling for pharmacy type.

resultsAmong 575 retail pharmacies contacted, 473 responded (82% response rate). The median cash price was significantly higher for big chain pharmacies than for independent pharmacies for tamsulosin ($66 vs. $15), finasteride ($68 vs. $15), oxybutynin immediate release ($49 vs. $35), and oxybutynin XL ($79 vs. $31) (all p < 0.05). When controlling for region, the median and 75

conclusionCompared to independent pharmacies, big chain pharmacies charged significantly more for generic BPH medications to uninsured patients. However, independent pharmacies demonstrated more regional variation in their pricing.

Indexed as

Costs and Cost AnalysisDrugs, GenericFinasterideHumansMaleMandelic AcidsPennsylvaniaProstatic HyperplasiaTamsulosinDrugs, GenericFinasterideMandelic AcidsoxybutyninTamsulosin

Identifiers

PMID32961225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.