Evidence map›Paper›PMID 32961080›Full record

ArticleHuman vaccines & immunotherapeutics2021

Prevalence and genotype distribution of human papillomavirus among women with cervical lesions in Shenzhen city, China.

Qingfeng Mai, Xiaohan Yang, Huan Cheng, Genghang Wu, Zikun Wu

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qingfeng MaiDepartment of Clinical Laboratory, University of Chinese Academy of Sciences Shenzhen Hospital, Shenzhen, People's Republic of China.
Xiaohan YangMedical Genetic Centre, Guangdong Women and Children's Hospital, Guangzhou Medical University, Guangzhou, People's Republic of China.ORCID 0000-0001-9896-1392
Huan ChengDepartment of Clinical Laboratory, University of Chinese Academy of Sciences Shenzhen Hospital, Shenzhen, People's Republic of China.
Genghang WuMedical Genetic Centre, Guangdong Women and Children's Hospital, Guangzhou Medical University, Guangzhou, People's Republic of China.
Zikun WuDepartment of Clinical Laboratory, University of Chinese Academy of Sciences Shenzhen Hospital, Shenzhen, People's Republic of China.
University of Chinese Academy of Sciences · CNGuangdong Province Women and Children Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is currently a lack of sufficient data on human papillomavirus (HPV)-attributable cervical carcinoma in China. Accordingly, we aimed to determine the prevalence and genotype distribution of HPV among women with cervical lesions in Shenzhen, in order to evaluate the potential benefit of HPV vaccination programs and inform cervical cancer control policies. We enrolled 5,255 patients who were admitted to the University of Chinese Academy of Sciences Shenzhen Hospital from January 2017 to December 2019. The HPV prevalence and genotype distribution were analyzed using the 21 HPV GenoArray diagnostic assay. A total of 937/5,255 patients showed HPV-positivity (prevalence rate 17.83%), of whom 85.81% (804/937) had high-risk HPV infection. HPV52 was the most prevalent genotype (4.72%, 248/5,255), followed by HPV58 (3.04%, 160/5,255), and HPV16 (2.72%, 143/5,255). The HPV prevalence rates among women with a normal cervix, low-grade intraepithelial lesions, high-grade intraepithelial lesions, invasive cervical cancer, and other characteristics were 15.63% (50/320), 58.65% (61/104), 80.00% (44/55), 88.57% (31/35), and 15.84% (751/4,741), respectively. HPV16, HPV18, and HPV52 accounted for the majority of cervical lesions, and the infection rates of HPV16 and HPV18 gradually increased with intraepithelial lesion progression (both

Indexed as

AlphapapillomavirusPapillomavirus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsChinaEarly Detection of CancerFemaleGenotypeHumansPapillomaviridaePrevalencecarcinomacervical intraepithelial lesiongenotype distributionHuman papillomavirusprevalence

Identifiers

PMID32961080
PMCPMC8018457
OpenAlexW3088324158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.