ArticleApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2021
Effect of local cold application during exercise on gene expression related to mitochondrial homeostasis.
Article in Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Cooling of male rat skeletal muscle during endurance-like contraction attenuates contraction-induced PGC-1α mRNA expression.Physiological reports · 2023Article
- The isolated effects of local cold application on proteolytic and myogenic signaling.Cryobiology · 2023Article
- Influence of Local Muscle Cooling on Mitochondrial-Related Gene Expression at Rest.International journal of environmental research and public health · 2022Article
- Effect of cold ambient temperature on heat flux, skin temperature, and thermal sensation at different body parts in elite biathletes.Frontiers in sports and active living · 2022Article
- Effect of local heat application during exercise on gene expression related to mitochondrial homeostasis.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Exercise training increases mitochondrial content in active skeletal muscle. Previous work suggests that mitochondrial-related genes respond favorably to exercise in cold environments. However, the impact of localized tissue cooling is unknown. The purpose of this study was to determine the impact of local muscle cooling during endurance exercise on human skeletal muscle mitochondrial-related gene expression. Twelve subjects (age, 28 ± 6 years) cycled at 65% peak power output. One leg was cooled (C) for 30 min before and during exercise with a thermal wrap while the other leg was wrapped but not cooled, room temperature (RT). Muscle biopsies were taken from each vastus lateralis before and 4 h after exercise for the analysis of gene expression. Muscle temperature was lower in the C (29.2 ± 0.7 °C) than the RT (34.1 ± 0.3 °C) condition after pre-cooling for 30 min before exercise (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.