ArticleAngewandte Chemie (International ed. in English)2021
Shear Stress-Responsive Polymersome Nanoreactors Inspired by the Marine Bioluminescence of Dinoflagellates.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 47 citations in OpenAlex.
- Wavelength-dependent feedback behavior in light-gated polymersome nanoreactors.Nature communications · 2026Article
- Mechanically Active Supramolecular Systems.Small science · 2024Article
- Shape Transformation of Polymer Vesicles.Accounts of materials research · 2024Article
- Dissipative Particle Dynamic Simulation on Self-Assembly of Symmetric CBABC Pentablock Terpolymers in Solution.Materials (Basel, Switzerland) · 2023Article
- Differences in Human Plasma Protein Interactions between Various Polymersomes and Stealth Liposomes as Observed by Fluorescence Correlation Spectroscopy.Macromolecular bioscience · 2023Article
- CES1-Triggered Liver-Specific Cargo Release of CRISPR/Cas9 Elements by Cationic Triadic Copolymeric Nanoparticles Targeting Gene Editing of PCSK9 for Hyperlipidemia Amelioration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Polymersome-based protein drug delivery - quo vadis?Chemical Society reviews · 2023Review
- Photoswitchable gating of non-equilibrium enzymatic feedback in chemically communicating polymersome nanoreactors.Nature chemistry · 2023Article
- Biocatalytic Synthesis Using Self-Assembled Polymeric Nano- and Microreactors.Angewandte Chemie (International ed. in English) · 2022Review
- Microliter Scale Synthesis of Luciferase-Encapsulated Polymersomes as Artificial Organelles for Optogenetic Modulation of Cardiomyocyte Beating.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Recent advances in mechanical force-responsive drug delivery systems.Nanoscale advances · 2022Review
- Kinetic Processes in Enzymatic Nanoreactors for In Vivo Detoxification.Biomedicines · 2022Article
- Single and Multiple Stimuli-Responsive Polymer Particles for Controlled Drug Delivery.Pharmaceutics · 2022Review
- Chemo-Biocascade Reactions Enabled by Metal-Organic Framework Micro-Nanoreactor.Research (Washington, D.C.) · 2022Article
- Shear Stress-Responsive Polymersome Nanoreactors Inspired by the Marine Bioluminescence of Dinoflagellates.Angewandte Chemie (International ed. in English) · 2021Article
- Controlled Dendrimersome Nanoreactor System for Localized Hypochlorite-Induced Killing of Bacteria.ACS nano · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Some marine plankton called dinoflagellates emit light in response to the movement of surrounding water, resulting in a phenomenon called milky seas or sea sparkle. The underlying concept, a shear-stress induced permeabilisation of biocatalytic reaction compartments, is transferred to polymer-based nanoreactors. Amphiphilic block copolymers that carry nucleobases in their hydrophobic block are self-assembled into polymersomes. The membrane of the vesicles can be transiently switched between an impermeable and a semipermeable state by shear forces occurring in flow or during turbulent mixing of polymersome dispersions. Nucleobase pairs in the hydrophobic leaflet separate when mechanical force is applied, exposing their hydrogen bonding motifs and therefore making the membrane less hydrophobic and more permeable for water soluble compounds. This polarity switch is used to release payload of the polymersomes on demand, and to activate biocatalytic reactions in the interior of the polymersomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.