Evidence map›Paper›PMID 32960605›Full record

ArticleJournal of medicinal chemistry2020

Ultrapotent Inhibitor of

George A Naclerio, Nader S Abutaleb, Daoyi Li, Mohamed N Seleem, Herman O Sintim

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 35 citations in OpenAlex.

  1. Incorporation of the Trifluoromethylthio Group (CFThe Journal of organic chemistry · 2026
    Review
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  13. The state of play of rodent models for the study ofJournal of medical microbiology · 2024
    Review
  14. Molecular docking, dynamics andBioinformation · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment ofJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

George A NaclerioChemistry Department, Institute for Drug Discovery, Purdue University, West Lafayette, Indiana 47907, United States.
Nader S AbutalebDepartment of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana 47907, United States.ORCID 0000-0003-1730-4150
Daoyi LiDepartment of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana 47907, United States.
Mohamed N SeleemDepartment of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana 47907, United States.ORCID 0000-0003-0939-0458
Herman O SintimChemistry Department, Institute for Drug Discovery, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-2280-9359
Purdue University West Lafayette · US

Funding

Repurposing auranofin and ebselen for treatment of multidrug resistant pathogensR01AI130186 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SELEEM, MOHAMED · 2017 to 2021
$2.3M
Drug Discovery in Infectious Disease TrainingT32AI148103 · NIAID · PURDUE UNIVERSITY · PI STAHELIN, ROBERT VIRGIL, YEO, YOON · 2020 to 2024
$949k
NIAID NIH HHS R01 AI130186NIAID NIH HHS T32 AI148103
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsCaco-2 CellsClostridioides difficileDose-Response Relationship, DrugDrug DiscoveryGastrointestinal MicrobiomeHumansMiceMicrobial Sensitivity TestsMolecular StructureStructure-Activity RelationshipAnti-Bacterial Agents

Identifiers

PMID32960605
PMCPMC9064041
OpenAlexW3088245433

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.