Evidence map›Paper›PMID 32960526›Full record

ArticleJBRA assisted reproduction2021

Which ovarian reserve marker relates to embryo quality on day 3 and blastocyst; age, AFC, AMH?

Juliano Brum Scheffer, Rafaela Friche de Carvalho, Ana Paula de Souza Aguiar, Iole Joana Moreira Machado, Juliana Baumgratz Franca, Daniel Mendez Lozano, Renato Fanchin

Open access · bronzeAbstract read
In one paragraph

Article in JBRA assisted reproduction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. The Oocyte/Antral Follicle Count Index: Does Maximizing Oocyte Yield Translate Into Better Assisted Reproductive Technology Outcomes?Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
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  14. Observational
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  16. Effects of environmental, social and surgical factors on ovarian reserve: Implications for age-relative female fertility.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021
    Article
  17. Anti-Müllerian Hormone and OPU-ICSI Outcome in the Mare.Animals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Juliano Brum SchefferIBRRA - Brazilian Institute of Assisted Reproduction, Belo Horizonte, Brazil.
Rafaela Friche de CarvalhoIBRRA - Brazilian Institute of Assisted Reproduction, Belo Horizonte, Brazil.
Ana Paula de Souza AguiarIBRRA - Brazilian Institute of Assisted Reproduction, Belo Horizonte, Brazil.
Iole Joana Moreira MachadoIBRRA - Brazilian Institute of Assisted Reproduction, Belo Horizonte, Brazil.
Juliana Baumgratz FrancaIBRRA - Brazilian Institute of Assisted Reproduction, Belo Horizonte, Brazil.
Daniel Mendez LozanoSchool of Medicine, Tecnologico de Monterrey and Center for Reproductive Medicine CREASIS, San Pedro Monterrey, Mexico.
Renato FanchinProfesseur des Universites - Praticien Hospitalier en Medecine de la Reproduction, France; Hopital Foch, France.
Hôpital Foch · FRTecnológico de Monterrey · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present prospective study was to evaluate which ovarian reserve marker would be more reliable as the quality of the A + B embryos (day 3 and blastocyst).

methodsWe ran a prospective study with 124 infertile women, aged 24-48 years, from 2017 to 2018. The patients were divided into 3 groups according to age and the subgroups were compared for AMH, AFC, number of A+B embryos. New division of the 3 groups was performed based on the AMH, and the subgroups were compared for age, AFC and number of A+B embryos. Finally, we divided the patients into 3 groups, based on the AFC, and we compared the subgroups for age, AMH and number of A+B embryos. P<0.05 was considered statistically significant.

resultsWhen the 124 patients were divided according to age, we found a significant fall in an A+B embryo quality (day3; blastocyst) after 35 years (p<0.038; p<0.035), and more severely after 37 years (p<0.032; p<0.027). When the 124 patients were divided according to AMH, there was a significant fall in A+B embryo quality (day 3; blastocyst), with AMH<1ng/ml (p<0.023; p<0.021). When the 124 patients were divided according to AFC, there was a significant fall in A+B embryo quality (day 3; blastocyst) with AFC<7 (p<0.025; p<0.023). These markers had significant associations with embryo quality (p<0.005).

conclusionAge, AFC and AMH have significant associations with A +B embryo quality on day 3 and blastocyst.

Indexed as

Infertility, FemaleOvarian ReserveAdultAnti-Mullerian HormoneBlastocystFemaleHumansOvarian FollicleProspective StudiesAnti-Mullerian HormoneageAMHantral follicle countembryo qualityovarian reserve

Identifiers

PMID32960526
PMCPMC7863095
OpenAlexW3088515969

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.