Evidence map›Paper›PMID 32960394›Full record

SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021

Patient-reported outcomes in non-muscle invasive bladder cancer: a mixed-methods systematic review.

Claudia Rutherford, Manish I Patel, Margaret-Ann Tait, David P Smith, Daniel S J Costa, Shomik Sengupta, Madeleine T King

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  8. Review
  9. Introduction to the special section "Reducing research waste in (health-related) quality of life research".Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Claudia RutherfordFaculty of Science, School of Psychology, University of Sydney, Sydney, NSW, Australia. claudia.rutherford@sydney.edu.au.ORCID http://orcid.org/0000-0002-4637-4572
Manish I PatelSydney Medical School, Discipline of Surgery, University of Sydney, Sydney, NSW, Australia.
Margaret-Ann TaitFaculty of Science, School of Psychology, University of Sydney, Sydney, NSW, Australia.
David P SmithCancer Research Division, Cancer Council New South Wales, Sydney, NSW, Australia.
Daniel S J CostaFaculty of Science, School of Psychology, University of Sydney, Sydney, NSW, Australia.
Shomik SenguptaEastern Health Clinical School, Monash University, Box Hill, Vic, Australia.
Madeleine T KingFaculty of Science, School of Psychology, University of Sydney, Sydney, NSW, Australia.
The University of Sydney · AUEastern Health · AUGriffith University · AU

Funding

Cancer Institute NSW 10/ECF/2-29
6 · The paper itself

Abstract

objectiveNon-muscle invasive bladder cancer (NMIBC) is a chronic condition requiring repeated treatment and endoscopic examinations that can occur life-long. In this context, patient-reported outcomes (PROs) are important considerations to patients and managing clinicians. We undertook a systematic review to synthesise PRO results relevant to NMIBC treatment to explore trajectories overtime and differences between treatment options.

methodsWe searched databases AMED, MEDLINE, EMbase, PsycINFO, Web of Knowledge and Scopus (inception to 5th December 2019), reference lists and contacted key authors to identify studies that reported PROs after NMIBC treatment. Two reviewers independently applied inclusion and quality criteria and extracted findings. Results for PROs were synthesised for treatment groups across three time periods: acute/during induction therapy; during maintenance therapy; and long-term follow-up (> 1 year).

resultsOf 3193 papers screened, 29 were eligible. These provided evidence about induction treatment effects, but few reported maintenance or long-term evidence, and evidence about differences between NMIBC treatment options was lacking. A range of symptoms (pain in bladder area, urinary frequency and urgency, pain or burning during urination) were commonly experienced during and soon after treatment for NMIBC. Less common symptoms included fatigue, disrupted sleep and gastrointestinal problems.

conclusionsTreatments for NMIBC can cause symptoms and functional impairment during the acute treatment phase and reduce quality of life. Clinicians should be aware of these impairments to prepare patients for short-term sequelae and enable those with treatment options to exercise preferences in choosing among them. However, gaps in current evidence limit our understanding of PRO trajectories from diagnosis through to long-term survivorship and treatment effects.

Indexed as

Patient Reported Outcome MeasuresFemaleHumansMaleQuality of LifeUrinary Bladder NeoplasmsEarly bladder cancerNon-muscle invasive bladder cancerPatient-reported outcomesQuality of lifeSystematic review

Identifiers

PMID32960394
OpenAlexW3087518925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.