ArticleActa neurochirurgica2021
How to avoid pneumocephalus in deep brain stimulation surgery? Analysis of potential risk factors in a series of 100 consecutive patients.
Article in Acta neurochirurgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Pneumocephalus after deep brain stimulation in Parkinson's disease: The role of brain volume in brain shift.Surgical neurology international · 2026Article
- Article
- Intraoperative 3D fluoroscopy accurately predicts final electrode position in deep brain stimulation surgery.Acta neurochirurgica · 2024Article
- Complications of deep brain stimulation in Parkinson's disease: a single-center experience of 517 consecutive cases.Acta neurochirurgica · 2023Article
- MER and increased operative time are not risk factors for the formation of pneumocephalus during DBS.Scientific reports · 2023Article
- Subdural Effusion Evolves into Chronic Subdural Hematoma after Deep Brain Stimulation Surgery: Case Report and Review of the Literature.Brain sciences · 2022Article
- Comparison of dural puncture and dural incision in deep brain stimulation surgery: A simple but worthwhile technique modification.Frontiers in neuroscience · 2022Article
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccuracy of lead placement is the key to success in deep brain stimulation (DBS). Precise anatomic stereotactic planning usually is based on stable perioperative anatomy. Pneumocephalus due to intraoperative CSF loss is a common procedure-related phenomenon which could lead to brain shift and targeting inaccuracy. The aim of this study was to evaluate potential risk factors of pneumocephalus in DBS surgery.
methodsWe performed a retrospective single-center analysis in patients undergoing bilateral DBS. We quantified the amount of pneumocephalus by postoperative CT scans and corrected the data for accompanying brain atrophy by an MRI-based score. Automated computerized segmentation algorithms from a dedicated software were used. As potential risk factors, we evaluated the impact of trephination size, the number of electrode tracks, length of surgery, intraoperative blood pressure, and brain atrophy.
resultsWe included 100 consecutive patients that underwent awake DBS with intraoperative neurophysiological testing. Systolic and mean arterial blood pressure showed a substantial impact with an inverse correlation, indicating that lower blood pressure is associated with higher volume of pneumocephalus. Furthermore, the length of surgery was clearly correlated to pneumocephalus.
conclusionOur analysis identifies intraoperative systolic and mean arterial blood pressure as important risk factors for pneumocephalus in awake stereotactic surgery.
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