SynthesisThe American journal of sports medicine2021
Return to Physical Activity After High Tibial Osteotomy or Unicompartmental Knee Arthroplasty: A Systematic Review and Pooling Data Analysis.
Synthesis in The American journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Comparison of Unicompartmental Knee Arthroplasty Versus High Tibial Osteotomy for Medial Knee Osteoarthritis: An Updated Meta-Analysis of 56,000 Patients.Orthopaedic surgery · 2025Pooled it
- Surgical interventions for symptomatic knee osteoarthritis: a network meta-analysis of randomized control trials.BMC musculoskeletal disorders · 2023Pooled it
- Unicompartmental knee arthroplasty is associated with lower pain levels but inferior range of motion, compared with high tibial osteotomy: a systematic overview of meta-analyses.Journal of orthopaedic surgery and research · 2022Pooled it
- Effect of Tranexamic Acid on Blood Management during a High Tibial Osteotomy: A Systematic Review and Meta-analysis.Orthopaedic surgery · 2022Pooled it
- Physical activity after unicompartmental knee arthroplasty: Long-term participation, activity volume and patient-reported limitations.Journal of experimental orthopaedics · 2026Article
- How to choose treatment for patients who are eligible for both unicompartmental knee arthroplasty and high tibial osteotomy?Journal of orthopaedic translation · 2026Review
- Knee extensor strength normalised to body weight is associated with patient-reported outcomes at 12 months after open-wedge high tibial osteotomy.Journal of experimental orthopaedics · 2026Article
- Advances in the pathology and treatment of osteoarthritis.Journal of advanced research · 2025Review
- High Tibial Osteotomy (HTO), Unicompartmental Knee Arthroplasty (UKA), and Proximal Fibular Osteotomy (PFO) for Medial-Compartment Knee Osteoarthritis: A Narrative Review of Comparative Mechanisms, Clinical Outcomes, and Decision-Making.Journal of clinical medicine · 2025Review
- Influence of Alignment Changes in Different Planes During Supra-Tubercular Biplanar Medial Opening Wedge High Tibial Osteotomy on Tibial Tubercle-Trochlear Groove Distance.Orthopaedic surgery · 2025Article
- Combined High Tibial Osteotomy and Transtibial Drilling of Tibial and Femoral Medial Compartment Cartilage Defect of the Knee.Arthroscopy techniques · 2025Article
- Spacer-type tibial osteotomy versus open wedge high tibial osteotomy and unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3-4 medial unicompartmental knee osteoarthritis in patients younger than 65 years.Journal of orthopaedic surgery and research · 2025Article
- Differential effects of tibia varus deformity on clinical outcomes following high tibial osteotomy and unicompartmental knee arthroplasty for moderate medial compartment osteoarthritis with moderate varus alignment.Archives of orthopaedic and trauma surgery · 2025Article
- Moldable self-setting and bioactive bone wax for bone hemostasis and defect repair.Journal of orthopaedic translation · 2025Article
- Anti-Inflammatory Modified Fuzi Decoction Antagonizes Synovial TNF-α/TRAF2/NF-κB Signaling to Remedy Osteoarthritis.Drug design, development and therapy · 2025Article
- BEST PROSTHESIS FOR UNICOMPARTMENTAL KNEE ARTHROSIS: FIXED OR MOBILE?Acta ortopedica brasileira · 2025Article
- Opening wedge high tibial osteotomy yields comparable to superior outcomes to unicompartmental knee arthroplasty at 2 years of follow-up in patients suffering from Ahlbäck III knee osteoarthritis: A propensity score-matched analysis.Journal of experimental orthopaedics · 2024Article
- Comparison of the indications for high tibial osteotomy and double-level osteotomy for the correction of diverse lower-leg deformities in an Asian population with medial compartment osteoarthritis: a retrospective observational study.International orthopaedics · 2024Observational
- Annual Trends of High Tibial Osteotomy: Analysis of an Official Registry in Italy.Medicina (Kaunas, Lithuania) · 2024Article
- Age-stratified analysis of HTO and UKA clinical effects in cross-indicated anterior medial osteoarthritis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe 2 most common definitive surgical interventions currently performed for the treatment of medial osteoarthritis of the knee are medial opening wedge high tibial osteotomy (HTO) and medial unicompartmental knee arthroplasty (UKA). Research exists to suggest that physically active patients may be suitably indicated for either procedure despite HTO being historically indicated in active patients and UKA being more appropriate for sedentary individuals. PURPOSE: To help consolidate the current indications for both procedures regarding physical activity and to ensure that they are based on the best information presently available. STUDY
designSystematic review.
methodsA search of the literature via the MEDLINE, Embase, and PubMed databases was conducted independently by 2 reviewers in accordance with the PRISMA (Preferred Reporting Items for Systematic Meta-Analyses) guidelines. Studies that reported patient physical activity levels with the Tegner activity score were eligible for inclusion. Patient demographics, operative variables, and patient-reported outcome scores were abstracted from the included studies.
resultsThirteen eligible studies were included, consisting of 401 knees that received HTO (399 patients) and 1622 that received UKA (1400 patients). The patients' mean age at surgery was 48.4 years for the HTO group and 60.6 years for the UKA group. Mean follow-up was 46.6 months (HTO) and 53.4 months (UKA). All outcome scores demonstrated an equal or improved score for activity and knee function regardless of the operation performed. Operative variables during HTO had a larger effect on outcome than during UKA.
conclusionPatients who underwent HTO were more physically active pre- and postoperatively, but patients undergoing UKA experienced an overall greater increase in their physical activity levels and knee function according to Tegner and Lysholm scores. Activity after HTO may be influenced by operative factors such as the implant used and the decision to include a graft material in the osteotomy gap, although this requires further research. Some studies found that patients were able to return to physical activity postoperatively despite having an age or body mass index that would traditionally be a relative contraindication for HTO or UKA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.