Evidence map›Paper›PMID 32959985›Full record

ArticlePediatric blood & cancer2021

Fatal capillary leak syndrome in a child with acute lymphoblastic leukemia treated with moxetumomab pasudotox for pre-transplant minimal residual disease reduction.

Nirali N Shah, Jennifer Schneiderman, Denison Kuruvilla, Deepa Bhojwani, Terry J Fry, Paul L Martin, Kirk R Schultz, Lewis B Silverman, James A Whitlock, Brent Wood and 6 more

Open access · greenAbstract readCase ReportsLetter
In one paragraph

Article in Pediatric blood & cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Systemic capillary leak syndrome.Nature reviews. Disease primers · 2024
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 3 countries.

Nirali N ShahPediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0002-8474-9080
Jennifer SchneidermanPediatric Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Denison KuruvillaClinical Pharmacology and Safety Sciences, AstraZeneca, San Francisco, California.
Deepa BhojwaniPediatric Hematology-Oncology, Children's Hospital Los Angeles, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Terry J FryPediatric Oncology, Children's Hospital Colorado, Denver, Colorado.
Paul L MartinPediatric Oncology, Duke University Medical Center, Durham, North Carolina.
Kirk R SchultzDivision of Hematology and Oncology, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.
Lewis B SilvermanPediatric Hematology and Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts.
James A WhitlockHematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
Brent WoodDepartment of Pathology, University of Washington, Seattle, Washington.
Inna VainshteinClinical Pharmacology and Safety Sciences, AstraZeneca, San Francisco, California.
Alexia AdamsNational Marrow Donor Program/Be the Match, Minneapolis, Minnesota.
Dennis ConferNational Marrow Donor Program/Be the Match, Minneapolis, Minnesota.
Michael A PulsipherPediatric Hematology-Oncology, Children's Hospital Los Angeles, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.ORCID 0000-0003-3030-8420
Sonali ChaudhuryPediatric Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Alan S WaynePediatric Hematology-Oncology, Children's Hospital Los Angeles, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
University of Southern California · USAstraZeneca (Australia) · AUNational Marrow Donor Program · USNorthwestern University · USBC Children's Hospital · CABoston Children's Hospital · USChildren's Hospital Colorado · USDuke Medical Center · USHospital for Sick Children · CANational Institutes of Health · USUniversity of Washington · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
Immunotherapeutic approaches to treat pediatric hematologic malignanciesZIABC011823 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI SHAH, NIRALI · 2019 to 2025
$6.1M
Unrelated Donor BMT vs. Immune Suppression for Newly Diagnosed Severe Aplastic Anemia in Children and Young Adults: BMT CTN Core Center Renewal for the Pediatric Blood and Marrow Transplant ConsortiumUG1HL069254 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI KEAN, LESLIE S · 2017 to 2023
$1.3M
NCI NIH HHS P30 CA014089NHLBI NIH HHS UG1 HL069254
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ToxinsCapillary Leak SyndromeChildExotoxinsFatal OutcomeFemaleHumansImmunotoxinsNeoplasm, ResidualPrecursor Cell Lymphoblastic Leukemia-LymphomaBacterial ToxinsExotoxinsimmunotoxin HA22Immunotoxins

Identifiers

PMID32959985
PMCPMC12032528
OpenAlexW3087490497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.