Evidence map›Paper›PMID 32958898›Full record

ArticleNature biomedical engineering2020

Rapid prototyping of soft bioelectronic implants for use as neuromuscular interfaces.

Dzmitry Afanasenkau, Daria Kalinina, Vsevolod Lyakhovetskii, Christoph Tondera, Oleg Gorsky, Seyyed Moosavi, Natalia Pavlova, Natalia Merkulyeva, Allan V Kalueff, Ivan R Minev and 1 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 148 citations in OpenAlex.

  1. Article
  2. Article
  3. Conductive Hydrogels for Exogenous Sensing and Cell Fate Control.Advanced materials (Deerfield Beach, Fla.) · 2026
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  17. Review
  18. Review
  19. Motion artefact management for soft bioelectronics.Nature reviews bioengineering · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Dzmitry Afanasenkau *Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Dresden, Germany.
Daria Kalinina *Institute of Translational Biomedicine, Saint-Petersburg State University, Saint-Petersburg, Russia.
Vsevolod LyakhovetskiiPavlov Institute of Physiology, Russian Academy of Sciences, Saint-Petersburg, Russia.
Christoph TonderaBiotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Dresden, Germany.
Oleg GorskyInstitute of Translational Biomedicine, Saint-Petersburg State University, Saint-Petersburg, Russia.
Seyyed MoosaviBiotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Dresden, Germany.
Natalia PavlovaInstitute of Translational Biomedicine, Saint-Petersburg State University, Saint-Petersburg, Russia.
Natalia MerkulyevaInstitute of Translational Biomedicine, Saint-Petersburg State University, Saint-Petersburg, Russia.
Allan V KalueffInstitute of Translational Biomedicine, Saint-Petersburg State University, Saint-Petersburg, Russia.
Ivan R MinevBiotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Dresden, Germany. i.minev@sheffield.ac.uk.ORCID http://orcid.org/0000-0003-2055-7386
Pavel MusienkoInstitute of Translational Biomedicine, Saint-Petersburg State University, Saint-Petersburg, Russia. p.musienko@spbu.ru.ORCID http://orcid.org/0000-0002-7324-9021
St Petersburg University · RUCenter for Systems Biology Dresden · DEPavlov Institute of Physiology of the Russian Academy of Sciences · RUUral Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromuscular interfaces are required to translate bioelectronic technologies for application in clinical medicine. Here, by leveraging the robotically controlled ink-jet deposition of low-viscosity conductive inks, extrusion of insulating silicone pastes and in situ activation of electrode surfaces via cold-air plasma, we show that soft biocompatible materials can be rapidly printed for the on-demand prototyping of customized electrode arrays well adjusted to specific anatomical environments, functions and experimental models. We also show, with the monitoring and activation of neuronal pathways in the brain, spinal cord and neuromuscular system of cats, rats and zebrafish, that the printed bioelectronic interfaces allow for long-term integration and functional stability. This technology might enable personalized bioelectronics for neuroprosthetic applications.

Indexed as

Biocompatible MaterialsPrinting, Three-DimensionalProstheses and ImplantsAnimalsCatsDielectric SpectroscopyElectric StimulationEquipment DesignFemaleInkMaleNeuromuscular MonitoringRats, WistarSciatic NerveSpinal CordUrinary BladderBiocompatible Materials

Identifiers

PMID32958898
OpenAlexW3087636483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.