ArticleNature communications2020
Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
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- Non-Coding RNAs as Critical Modulators of Cholesterol Metabolism in Cancer.Biomedicines · 2025Review
- miR-210 locus deletion disrupts cellular homeostasis: an integrated genetic study.Scientific reports · 2025Article
- MIR193BHG inhibits the proliferation, migration and invasion of trophoblasts by upregulating p53.Experimental and therapeutic medicine · 2024Article
- Functional characterization of human genomic variation linked to polygenic diseases.Trends in genetics : TIG · 2023Review
- Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase.eLife · 2023Article
- Hypoxia signaling: Challenges and opportunities for cancer therapy.Seminars in cancer biology · 2022Review
- A novel imatinib-upregulated long noncoding RNA plays a critical role in inhibition of tumor growth induced by Abl oncogenes.Molecular cancer · 2022Article
- Prognostication of Pancreatic Cancer Using The Cancer Genome Atlas Based Ferroptosis-Related Long Non-Coding RNAs.Frontiers in genetics · 2022Article
- An epithelial-mesenchymal transition-related long non-coding RNA signature to predict overall survival and immune microenvironment in kidney renal clear cell carcinoma.Bioengineered · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
35 authors at 15 institutions in 6 countries.
Xue WuDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Cristina M NiculiteDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Mihai Bogdan PredaInstitute of Cellular Biology and Pathology "Nicolae Simionescu", Bucharest, Romania.
Annalisa RossiLaboratory of Molecular and Cellular Neurobiology, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.
Toma TebaldiLaboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.
Elena ButoiInstitute of Cellular Biology and Pathology "Nicolae Simionescu", Bucharest, Romania.
Mattie K WhiteDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Oana M TudoranThe Oncology Institute "Prof Dr. Ion Chiricuta", Cluj-Napoca, Romania.
Daniela N PetruscaDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Amber S JannaschMetabolite Profiling Facility, Bindley Bioscience Center, Purdue University, West Lafayette, IN, 47907, USA.
William P BoneDepartment of Genetics, Department of Systems Pharmacology and Translational Therapeutics, Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Xingyue ZongDepartment of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Fang FangDepartment of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Alexandrina BurlacuInstitute of Cellular Biology and Pathology "Nicolae Simionescu", Bucharest, Romania.
Michelle T PaulsenDepartments of Radiation Oncology and Environmental Health Sciences, Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Brad A HancockDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
George E SanduskyDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Sumegha MitraMelvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.
Melissa L FishelMelvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.ORCID http://orcid.org/0000-0002-9436-6382
Aaron BuechleinIndiana University Center for Genomics and Bioinformatics, Bloomington, IN, 47405, USA.
Cristina IvanCenter for RNA Interference and Non-coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0002-4848-0168
Spyros OikonomopoulosDepartment of Human Genetics, McGill University and Genome Quebec Innovation Centre, McGill University, Montréal, QC, Canada.
Myriam GorospeLaboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
Amber MosleyDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.ORCID http://orcid.org/0000-0001-5822-2894
Milan RadovichDepartments of Radiation Oncology and Environmental Health Sciences, Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Utpal P DavéDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.ORCID http://orcid.org/0000-0002-9416-1686
Jiannis RagoussisDepartment of Human Genetics, McGill University and Genome Quebec Innovation Centre, McGill University, Montréal, QC, Canada.ORCID http://orcid.org/0000-0002-8515-0934
Kenneth P NephewDepartment of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.ORCID http://orcid.org/0000-0003-2192-1346
Bernard MariCNRS, IPMC, FHU-OncoAge, Université Côte d'Azur, Valbonne, France.ORCID http://orcid.org/0000-0002-0422-9182
Alan McIntyreRogel Cancer Center, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID http://orcid.org/0000-0002-4791-7292
Heiko KonigDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Mats LjungmanDepartments of Radiation Oncology and Environmental Health Sciences, Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Diana L CousminerDivision of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Paolo MacchiLaboratory of Molecular and Cellular Neurobiology, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.
Mircea IvanDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. mivan@iu.edu.ORCID http://orcid.org/0000-0003-3424-6642
Indiana University School of MedicineIndiana University Health · USUniversity of Trento · ITMcGill Genome Centre · CAUniversity of Michigan · USCentre National de la Recherche Scientifique · FRChildren's Hospital of Philadelphia · USIndiana University Bloomington · USInstitute of Oncology Prof. Dr. Ion Chiricuta · ROInstitutul National Victor Babes · RONational Institutes of Health · USPurdue University West Lafayette · USThe University of Texas MD Anderson Cancer Center · USTranslational Therapeutics (United States) · USUniversity of Nottingham · GB
Funding
Short-Term Training Program In Biomedical SciencesT35HL110854 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Brittney-Shea Herbert, Catherine Rufatto Sears · 2012 to 2026
$3.4MThe Role of LMO2 in the Pathogenesis of T-cell LeukemiaR01CA207530 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI DAVE, UTPAL P · 2016 to 2020
$1.8MRole of Hypoxia-Induced miR-210 in Tumor MetabolismR01CA155332 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI IVAN, MIRCEA · 2011 to 2015
$1.7MGenetic determinants of puberty and later life health outcomesK99HD099330 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI COUSMINER, DIANA · 2019 to 2019
$132kBLRD VA I01 BX001799Medical Research Council MR/P010334/1NCI NIH HHS R01 CA155332NCI NIH HHS R01 CA207530NICHD NIH HHS K99 HD099330
Abstract
We hereby provide the initial portrait of lincNORS, a spliced lincRNA generated by the MIR193BHG locus, entirely distinct from the previously described miR-193b-365a tandem. While inducible by low O
Indexed as
HomeostasisBasic Helix-Loop-Helix ProteinsCell HypoxiaCell Line, TumorCell NucleusCholesterolEndothelial PAS Domain-Containing Protein 1EstrogensGene Expression RegulationGenome-Wide Association StudyHeterogeneous-Nuclear Ribonucleoprotein Group CHumansMCF-7 CellsOxygenPhenotypePolymorphism, Single NucleotideBasic Helix-Loop-Helix ProteinsCholesterolEndothelial PAS Domain-Containing Protein 1EstrogensHeterogeneous-Nuclear Ribonucleoprotein Group COxygenRALY protein, humanRNA, Long NoncodingSterols
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.