Evidence map›Paper›PMID 32958638›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Vitamin A aldehyde-taurine adduct and the visual cycle.

Hye Jin Kim, Jin Zhao, Janet R Sparrow

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. More insights from Abca4The Journal of biological chemistry · 2026
    Article
  2. Article
  3. Review
  4. Advances and therapeutic opportunities in visual cycle modulation.Progress in retinal and eye research · 2025
    Review
  5. Article
  6. Microsomal triglyceride transfer protein is necessary to maintain lipid homeostasis and retinal function.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hye Jin KimDepartment of Ophthalmology, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0001-7363-4053
Jin ZhaoDepartment of Ophthalmology, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0002-1934-6445
Janet R SparrowDepartment of Ophthalmology, Columbia University Medical Center, New York, NY 10032; jrs88@cumc.columbia.edu.ORCID 0000-0001-7448-5950
Columbia University Irving Medical Center · US

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
IMPACT OF LIPOFUSCIN IN RETINAL PIGMENT EPITHELIAL CELLSR01EY012951 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPARROW, JANET RUTHE · 2000 to 2024
$8.9M
Quantitative Fundus Autofluorescence in Retinal DisordersR01EY024091 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPARROW, JANET RUTHE · 2014 to 2022
$3.4M
NEI NIH HHS P30 EY019007NEI NIH HHS R01 EY012951NEI NIH HHS R01 EY024091
6 · The paper itself

Abstract

Visual pigment consists of opsin covalently linked to the vitamin A-derived chromophore, 11-

Indexed as

Animalscis-trans-IsomerasesHumansIsomerismLightMiceMice, Inbred BALB CMice, Inbred C57BLPhotoreceptor CellsRetinaRetinaldehydeRetinal Pigment EpitheliumRetinoid IsomerohydrolaseRetinoidsTaurinecis-trans-IsomerasesRetinaldehydeRetinoid IsomerohydrolaseRetinoidsTaurinephotoreceptor cellsretinal pigment epitheliumtaurinevisual cyclevitamin A

Identifiers

PMID32958638
PMCPMC7547175
OpenAlexW3087125681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.