Evidence map›Paper›PMID 32958587›Full record

Observational studyCancer prevention research (Philadelphia, Pa.)2021

Reducing Fatty Acid Oxidation Improves Cancer-free Survival in a Mouse Model of Li-Fraumeni Syndrome.

Ping-Yuan Wang, Jin Ma, Jie Li, Matthew F Starost, Michael J Wolfgang, Komudi Singh, Mehdi Pirooznia, Ju-Gyeong Kang, Paul M Hwang

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Cancer prevention research (Philadelphia, Pa.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ping-Yuan Wang *Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Jin Ma *Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Jie LiCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Matthew F StarostDivision of Veterinary Resources, NIH, Bethesda, Maryland.
Michael J WolfgangDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Komudi SinghBioinformatics and Computational Biology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Mehdi PiroozniaBioinformatics and Computational Biology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.ORCID 0000-0002-4210-6458
Ju-Gyeong KangCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Paul M HwangCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland. hwangp@mail.nih.gov.ORCID 0000-0002-5976-7834
National Heart Lung and Blood Institute · USJohns Hopkins University · USNational Institutes of Health · US

Funding

Mitochondrial regulation in cardiovascular and cancer biologyZIAHL005101 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI HWANG, PAUL M. · 2009 to 2025
$19.1M
Bioinformatics CoreZICHL006228 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI PIROOZNIA, MEHDI · 2017 to 2021
$6.6M
Genetic insights into cardiovascular function and diseaseZ01HL005101 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI HWANG, PAUL M. · 2005 to 2008
$4.4M
Intramural NIH HHS Z01 HL005101Intramural NIH HHS ZIA HL005101
6 · The paper itself

Abstract

Germline mutations of

Indexed as

AdolescentAdultAgedAged, 80 and overAnimalsCarcinogenesisCarnitine O-PalmitoyltransferaseCase-Control StudiesCells, CulturedDisease-Free SurvivalDisease Models, AnimalEnergy MetabolismFatty AcidsFemaleGene Knock-In TechniquesGenetic Predisposition to DiseaseCarnitine O-PalmitoyltransferaseFatty AcidsMyoglobinTP53 protein, humanTrp53 protein, mouseTumor Suppressor Protein p53

Identifiers

PMID32958587
PMCPMC7981282
OpenAlexW3087056508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.