Evidence map›Paper›PMID 32957971›Full record

Trial reportBMC medicine2020

Decreased costs and retained QoL due to the 'PACE Steps to Success' intervention in LTCFs: cost-effectiveness analysis of a randomized controlled trial.

Anne B Wichmann, Eddy M M Adang, Kris C P Vissers, Katarzyna Szczerbińska, Marika Kylänen, Sheila Payne, Giovanni Gambassi, Bregje D Onwuteaka-Philipsen, Tinne Smets, Lieve Van den Block and 4 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 6 countries.

Anne B WichmannIQ Health Care, Radboud Institute for Health Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands. Anne.Wichmann@radboudumc.nl.ORCID 0000-0003-0085-9782
Eddy M M AdangDepartment for Health Evidencef, Radboud University Medical Centre, Nijmegen, The Netherlands.
Kris C P VissersDepartment of Anaesthesiology, Pain and Palliative Medicine, Radboud University Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Katarzyna SzczerbińskaUnit for Research on Aging Society, Epidemiology and Preventive Medicine Chair, Jagiellonian University Medical College, Kraków, Poland.
Marika KylänenNational Institute for Health and Welfare, Helsinki, Finland.
Sheila PayneDivision of Health Research, Lancaster University, Lancaster, England.
Giovanni GambassiFaculty of Medicine and Surgery, Fondazione Policlinico Universitario A. Gemelli, IRCCS and Università Cattolica del Sacro Cuore, Rome, Italy.
Bregje D Onwuteaka-PhilipsenDepartment of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Tinne SmetsEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Brussel, Belgium.
Lieve Van den BlockEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Brussel, Belgium.
Luc DeliensEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Brussel, Belgium.
Myrra J F J Vernooij-DassenIQ Health Care, Radboud Institute for Health Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands.
Yvonne EngelsDepartment of Anaesthesiology, Pain and Palliative Medicine, Radboud University Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
PACE trial group
Radboud University Nijmegen · NLJagiellonian University · PLLancaster University · GBVrije Universiteit Brussel · BEAmsterdam University Medical Centers · NLFinnish Institute for Health and Welfare · FIUniversità Cattolica del Sacro Cuore · IT

Funding

Seventh Framework Programme 6031111
6 · The paper itself

Abstract

backgroundThe number of residents in long-term care facilities (LTCFs) in need of palliative care is growing in the Western world. Therefore, it is foreseen that significantly higher percentages of budgets will be spent on palliative care. However, cost-effectiveness analyses of palliative care interventions in these settings are lacking. Therefore, the objective of this paper was to assess the cost-effectiveness of the 'PACE Steps to Success' intervention. PACE (Palliative Care for Older People) is a 1-year palliative care programme aiming at integrating general palliative care into day-to-day routines in LTCFs, throughout seven EU countries.

methodsA cluster RCT was conducted. LTCFs were randomly assigned to intervention or usual care. LTCFs reported deaths of residents, about whom questionnaires were filled in retrospectively about resource use and quality of the last month of life. A health care perspective was adopted. Direct medical costs, QALYs based on the EQ-5D-5L and costs per quality increase measured with the QOD-LTC were outcome measures.

resultsAlthough outcomes on the EQ-5D-5L remained the same, a significant increase on the QOD-LTC (3.19 points, p value 0.00) and significant cost-savings were achieved in the intervention group (€983.28, p value 0.020). The cost reduction mainly resulted from decreased hospitalization-related costs (€919.51, p value 0.018).

conclusionsCosts decreased and QoL was retained due to the PACE Steps to Success intervention. Significant cost savings and improvement in quality of end of life (care) as measured with the QOD-LTC were achieved. A clinically relevant difference of almost 3 nights shorter hospitalizations in favour of the intervention group was found. This indicates that timely palliative care in the LTCF setting can prevent lengthy hospitalizations while retaining QoL. In line with earlier findings, we conclude that integrating general palliative care into daily routine in LTCFs can be cost-effective.

trial registrationISRCTN14741671 .

Indexed as

Aged, 80 and overCost-Benefit AnalysisFemaleHumansLong-Term CareMaleNursing HomesQuality of LifeRetrospective StudiesCost-benefit analysisNursing homesPalliative careTeaching

Identifiers

PMID32957971
PMCPMC7507669
OpenAlexW3087600244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.