Evidence map›Paper›PMID 32957602›Full record

ArticlePharmaceutics2020

Poly(Aspartic Acid) Functionalized Poly(ϵ-Caprolactone) Microspheres with Enhanced Hydroxyapatite Affinity as Bone Targeting Antibiotic Carriers.

Stijn G Rotman, Thomas F Moriarty, Benjamin Nottelet, Dirk W Grijpma, David Eglin, Olivier Guillaume

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Stijn G RotmanAO Research Institute Davos, 7270 Davos Platz, Switzerland.ORCID 0000-0002-6685-8312
Thomas F MoriartyAO Research Institute Davos, 7270 Davos Platz, Switzerland.ORCID 0000-0003-2307-0397
Benjamin NotteletIBMM, University of Montpellier, CNRS, ENSCM, 34093 Montpellier, France.ORCID 0000-0002-8577-9273
Dirk W GrijpmaDepartment of Biomaterials Science and Technology, Faculty of Science and Technology and Technical Medical Centre, University of Twente, 7522 NB Enschede, The Netherlands.ORCID 0000-0002-2678-2480
David EglinAO Research Institute Davos, 7270 Davos Platz, Switzerland.ORCID 0000-0002-8500-6887
Olivier GuillaumeInstitute of Materials Science and Technology, TU Wien, 1060 Vienna, Austria.ORCID 0000-0003-0735-113X
AO Foundation · CHÉcole Nationale Supérieure de Chimie de Montpellier · FRTU Wien · ATUniversity of Twente · NL

Funding

RENAL PATHOGENICITY OF ANTIDNA ANTIBODIESK08AR002015 · NIAMS · YESHIVA UNIVERSITY · PI PUTTERMAN, CHAIM · 1997 to 2001
$252k
AOTrauma Clinical Priority Program Bone Infection AR2015-04
6 · The paper itself

Abstract

Bone infection is a feared complication for patients with surgically fixed bone fractures and local antibiotic delivery is important in prophylaxis and treatment of these infections. Recent studies indicated that

Indexed as

bone infectionbone seeking agentsbone targetingdrug deliverypoly(aspartic acid)

Identifiers

PMID32957602
PMCPMC7559286
OpenAlexW3085380035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.