ArticleChildren (Basel, Switzerland)2020
Comparison of Blood Pressure and Kidney Markers between Adolescent Former Preterm Infants and Term Controls.
Article in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Kidney health outcomes in children born very prematurely compared to full-term counterparts: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- Pooled it
- Young adults born moderately to extremely preterm have higher eGFR and cystatin C compared to young adults born at term.Pediatric nephrology (Berlin, Germany) · 2026Article
- Renal consequences of prematurity and utility of serum uromodulin as a marker of kidney growth- a cross sectional single centre study.BMC nephrology · 2026Article
- Impact of growth hormone therapy on ambulatory blood pressure in small-for-gestational-age children.Annals of pediatric endocrinology & metabolism · 2026Article
- Early detection of kidney impairment in school-aged children born very preterm: a parallel use of traditional and modern biomarkers.Pediatric nephrology (Berlin, Germany) · 2026Article
- Reduced kidney function in very-low-birth-weight preterm infants at preschool age.Pediatric nephrology (Berlin, Germany) · 2025Article
- Long-Term Impact of Neonatal Acute Kidney Injury on Renal Function in Children Born Preterm: A Follow-Up Study.Children (Basel, Switzerland) · 2025Article
- Protein Biomarkers in Chronic Kidney Disease in Children-What Do We Know So Far?Journal of clinical medicine · 2023Review
- Special Issue: Prematurity, Preterm-Born Adults, and Long-Term Effects on Children and Adults.Children (Basel, Switzerland) · 2023Article
- Cardiovascular Morbidities in Adults Born Preterm: Getting to the Heart of the Matter!Children (Basel, Switzerland) · 2022Review
- Preterm Birth, Kidney Function and Cardiovascular Disease in Children and Adolescents.Children (Basel, Switzerland) · 2022Review
- Sexual Dimorphism of Corticosteroid Signaling during Kidney Development.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm infants are at an increased risk of developing hypertension and chronic kidney disease later in life. No recommendations exist for blood pressure (BP) and renal follow up for these patients.
aimTo compare BP and serum and urinary kidney markers between preterm-born adolescents and term-born controls.
methodsBP measurements in 51 preterm-born (≤32 weeks gestational age) and 82 term-born adolescents at the age of 10-15 years were conducted. Stepwise regression analysis explored the association between BP and participant characteristics. Kidney markers measured in the serum and urine were creatinine, neutrophil gelatinase-associated lipocalin (NGAL), and uromodulin. Kidney markers measured in the serum were cystatin C, beta-2 microglobulin, and beta trace protein.
resultsSystolic BP was significantly higher in preterm boys compared with term boys, but not in girls, and low birth weight was associated with higher BP in boys. In the preterm group, maternal hypertension/preeclampsia and adolescent height were associated with higher systolic BP. Serum creatinine and NGAL were significantly higher in the preterm group.
conclusionsOur study confirms an inverse sex-dependant relationship between birth weight and BP at adolescent age. The higher serum creatinine and NGAL in the preterm group may indicate that premature birth affects kidney function in the long term.
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Registered trials
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