Evidence map›Paper›PMID 32957201›Full record

ArticleJournal of the mechanical behavior of biomedical materials2020

Impact of superhydrophobicity on the fluid dynamics of a bileaflet mechanical heart valve.

Hoda Hatoum, Sravanthi Vallabhuneni, Arun Kumar Kota, David L Bark, Ketul C Popat, Lakshmi Prasad Dasi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hoda HatoumDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Sravanthi VallabhuneniDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC, USA.
Arun Kumar KotaDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC, USA.
David L BarkDepartment of Mechanical Engineering, Colorado State University, Fort Collins, CO, USA.
Ketul C PopatDepartment of Mechanical Engineering, Colorado State University, Fort Collins, CO, USA.
Lakshmi Prasad DasiDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA. Electronic address: lakshmi.dasi@gatech.edu.
Colorado State University · USGeorgia Institute of Technology · USNorth Carolina State University · US

Funding

Superhydrophobic Heart Valve ProsthesisR01HL135505 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2017 to 2020
$2.9M
Superomniphobic flow controlled prosthetic heart valveR21HL139208 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2018 to 2019
$408k
American Heart Association-American Stroke Association 19POST34380804NHLBI NIH HHS R01 HL135505NHLBI NIH HHS R21 HL139208
6 · The paper itself

Abstract

objectiveThe objective of this study is to evaluate the impact of superhydrophobic coating on the hemodynamics and turbulence characteristics of a bileaflet mechanical valve in the context of evaluating blood damage potential.

methodsTwo 3D printed bileaflet mechanical valves were hemodynamically tested in a pulse duplicator under physiological pressure and flow conditions. The leaflets of one of the two valves were sprayed with a superhydrophobic coating. Particle Image Velocimetry was performed. Pressure gradients (PG), effective orifice areas (EOA), Reynolds shear stresses (RSS) and instantaneous viscous shear stresses (VSS) were calculated.

results(a) Without SH coating, the PG was found to be 14.53 ± 0.7 mmHg and EOA 1.44 ± 0.06 cm

conclusionWith Reynolds Shear Stresses and instantaneous Viscous Shear Stresses being correlated with platelet damage, SH coating did not lead to their decrease. While SH coating is known to improve surface properties such as reduced platelet or clot adhesion, the relaxation of the slip condition does not necessarily improve overall hemodynamic performance for the bileaflet mechanical valve design.

Indexed as

Heart Valve ProsthesisHeart ValvesHemodynamicsHydrodynamicsModels, CardiovascularProsthesis DesignStress, MechanicalBlood damageReynolds shear stressSuperhydrophobicityTurbulenceViscous shear stress

Identifiers

PMID32957201
PMCPMC11046437
OpenAlexW3042164472

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.