Evidence map›Paper›PMID 32956997›Full record

ArticleTranslational oncology2020

A novel vitamin D gene therapy for acute myeloid leukemia.

Yi Xu, Kimberly Payne, Linh Hoang Gia Pham, Park Eunwoo, Jeffrey Xiao, David Chi, Justin Lyu, Rosalia Campion, Samiksha Wasnik, Il Seok Jeong and 8 more

Open access · goldAbstract read
In one paragraph

Article in Translational oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Yi XuDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA; Department of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
Kimberly PayneDepartment of Basic Sciences, Division of Anatomy, Loma Linda University, Loma Linda, CA, USA.
Linh Hoang Gia PhamDepartment of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
Park EunwooDepartment of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
Jeffrey XiaoDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA; Department of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
David ChiDepartment of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
Justin LyuDepartment of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
Rosalia CampionDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA.
Samiksha WasnikDepartment of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
Il Seok JeongDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA.
Xiaolei TangDepartment of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY, USA.
David Jeston BaylinkDepartment of Medicine, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA, USA.
Chien Shing ChenDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA.
Mark ReevesDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA.
Mojtaba AkhtariDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA.
Saied MirshahidiLoma Linda University Cancer Center Biospecimen Laboratory, Department of Medicine & Basic Sciences, Loma Linda, CA, USA.
Guido MarcucciGehr Family Center for Leukemia Research, Hematology Malignancies and Stem Cell Transplantation Institute, City of Hope Medical Center, Duarte, CA, USA.
Huynh CaoDepartment of Hematology and Oncology, Loma Linda University Cancer Center, Loma Linda, CA, USA. Electronic address: hcao@llu.edu.
Loma Linda University · USCity of Hope · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current treatment approaches for older adult patients with acute myeloid leukemia (AML) are often toxic and lack efficacy. Active vitamin D3 (1,25(OH)

Identifiers

PMID32956997
PMCPMC7509076
OpenAlexW3087335839

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.