Evidence map›Paper›PMID 32956979›Full record

ArticleCell calcium2020

Metabolite regulation of the mitochondrial calcium uniporter channel.

Dhanendra Tomar, John W Elrod

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. The two faces of mitochondrial CaJournal of physiology and biochemistry · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Mechano-energetic uncoupling in heart failure.Nature reviews. Cardiology · 2025
    Review
  8. Article
  9. AnPlant signaling & behavior · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Mitochondria in Pathological Cardiac Remodeling.Current opinion in physiology · 2022
    Article
  14. MICU3 regulates mitochondrial CaCell death & disease · 2021
    Article
  15. Dynamic Control of Mitochondrial CaFrontiers in cell and developmental biology · 2021
    Article
  16. Reduced reticulum-mitochondria CaBasic research in cardiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dhanendra TomarCenter for Translational Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA. Electronic address: dhtomar@temple.edu.
John W ElrodCenter for Translational Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA. Electronic address: elrod@temple.edu.
Temple University · US

Funding

Small and large animal surgery, physiology and histologyP01HL134608 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI Raj Kishore · 2017 to 2026
$21.0M
Targeting Pathways Involved in Cardiac Injury for Novel Repair StrategiesP01HL147841 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI KOCH, WALTER J. · 2020 to 2024
$11.4M
Molecular composition of the mitochondrial calcium uniporter and cardiac pathophysiologyR01HL142271 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI ELROD, JOHN WILLIAM, HAJNOCZKY, GYORGY · 2018 to 2021
$3.0M
Mechanisms of mitochondrial calcium exchange in heart failureR01HL123966 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2014 to 2018
$2.3M
Novel Molecular Mechanisms of Programmed NecrosisR01HL136954 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2017 to 2020
$1.6M
Impact of mitochondrial structure on cellular homeostasis and hepatic injuryK99DK120876 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI TOMAR, DHANENDRA · 2020 to 2021
$181k
NHLBI NIH HHS P01 HL134608NHLBI NIH HHS P01 HL147841NHLBI NIH HHS R01 HL123966NHLBI NIH HHS R01 HL136954NHLBI NIH HHS R01 HL142271NIDDK NIH HHS K99 DK120876
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

MetabolomeAutophagyCalciumCalcium ChannelsCitric Acid CycleEarly Growth Response Protein 1Energy MetabolismHumansIon Channel GatingMitochondriaSubstrate SpecificityCalciumCalcium ChannelsEarly Growth Response Protein 1mitochondrial calcium uniporterCalciumEnergeticsMCUMICU1MitochondriaMPCOXPHOSTCA cycleTCA substrates

Identifiers

PMID32956979
PMCPMC8017895
OpenAlexW3085113313

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.