Evidence map›Paper›PMID 32956644›Full record

ReviewEuropean journal of pharmacology2020

A review of medications used to control and improve the signs and symptoms of COVID-19 patients.

Kiavash Hushmandi, Saied Bokaie, Mehrdad Hashemi, Ebrahim Rahmani Moghadam, Mehdi Raei, Farid Hashemi, Mahdi Bagheri, Solomon Habtemariam, Seyed Mohammad Nabavi

Open access · greenAbstract readReview
In one paragraph

Review in European journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Oxidative Stress-Related Mechanisms in SARS-CoV-2 Infections.Oxidative medicine and cellular longevity · 2022
    Review
  2. COVID-19 pandemic in Uttarakhand, India: Environmental recovery or degradation?Journal of environmental chemical engineering · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Kiavash HushmandiDepartment of Food Hygiene and Quality Control, Division of Epidemiology & Zoonoses, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran. Electronic address: houshmandi.kia7@ut.ac.ir.
Saied BokaieDepartment of Food Hygiene and Quality Control, Division of Epidemiology & Zoonoses, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Mehrdad HashemiDepartment of Genetics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Ebrahim Rahmani MoghadamDepartment of Anatomical Sciences, School of Medicine, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Mehdi RaeiHealth Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: mehdi_r_d@yahoo.com.
Farid HashemiKazerun Health Technology Incubator, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahdi BagheriHealth Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Solomon HabtemariamPharmacognosy Research Laboratories and Herbal Analysis Services, University of Greenwich, Central Avenue, Chatham-Maritime, Kent, ME4 4TB, United Kingdom.
Seyed Mohammad NabaviApplied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Baqiyatallah University of Medical Sciences · IRShiraz University of Medical Sciences · IRUniversity of Tehran · IRBiotechnology Research Center · IRIslamic Azad University Medical Branch of Tehran · IRUniversity of Greenwich · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In December 2019, an unprecedented outbreak of pneumonia associated with a novel coronavirus disease 2019 (COVID-19) emerged in Wuhan City, Hubei province, China. The virus that caused the disease was officially named by the World Health Organization (WHO) as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). According to the high transmission rate of SARS-CoV-2, it became a global pandemic and public health emergency within few months. Since SARS-CoV-2 is genetically 80% homologous with the SARS-CoVs family, it is hypothesized that medications developed for the treatment of SARS-CoVs may be useful in the control and management of SARS-CoV-2. In this regard, some medication being tested in clinical trials and in vitro studies include anti-viral RNA polymerase inhibitors, HIV-protease inhibitors, anti-inflammatory agents, angiotensin converting enzyme type 2 (ACE 2) blockers, and some other novel medications. In this communication, we reviewed the general characteristics of medications, medical usage, mechanism of action, as well as SARS-CoV-2 related trials.

Indexed as

Anti-Inflammatory AgentsAntiviral AgentsChloroquineCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentDNA-Directed RNA PolymerasesHumansPandemicsPneumonia, ViralAnti-Inflammatory AgentsAntiviral AgentsChloroquineDNA-Directed RNA PolymerasesMedicationsNovel corona virusSARS-CoV-2

Identifiers

PMID32956644
PMCPMC7501068
OpenAlexW3087112250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.