Evidence map›Paper›PMID 32956623›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2020

Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m

Xiaochuan Liu, Gwendolyn Gonzalez, Xiaoxia Dai, Weili Miao, Jun Yuan, Ming Huang, David Bade, Lin Li, Yuxiang Sun, Yinsheng Wang

Open access · bronzeAbstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 122 citations in OpenAlex.

  1. METTL16 S-glutathionylation-triggered RNA mActa pharmacologica Sinica · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  6. Article
  7. Identification of AK4 and RHOC as potential oncogenes addicted by adult T cell leukemia.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Downregulation of the mThe Journal of biological chemistry · 2024
    Article
  14. Review
  15. Functions and mechanisms of RNA mInternational journal of oncology · 2024
    Review
  16. Targeting ROS in cancer: rationale and strategies.Nature reviews. Drug discovery · 2024
    Review
  17. Progression of mCell death discovery · 2024
    Review
  18. Review
  19. Role of NOncology reports · 2024
    Review
  20. Small molecule inhibitors targeting mJournal of hematology & oncology · 2024
    Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaochuan LiuDepartment of Chemistry, University of California, Riverside, Riverside, CA 92521, USA.
Gwendolyn GonzalezEnvironmental Toxicology Graduate Program, University of California, Riverside, Riverside, CA 92502, USA.
Xiaoxia DaiDepartment of Chemistry, University of California, Riverside, Riverside, CA 92521, USA.
Weili MiaoDepartment of Chemistry, University of California, Riverside, Riverside, CA 92521, USA.
Jun YuanEnvironmental Toxicology Graduate Program, University of California, Riverside, Riverside, CA 92502, USA.
Ming HuangEnvironmental Toxicology Graduate Program, University of California, Riverside, Riverside, CA 92502, USA.
David BadeEnvironmental Toxicology Graduate Program, University of California, Riverside, Riverside, CA 92502, USA.
Lin LiDepartment of Chemistry, University of California, Riverside, Riverside, CA 92521, USA.
Yuxiang SunDepartment of Chemistry, University of California, Riverside, Riverside, CA 92521, USA.
Yinsheng WangDepartment of Chemistry, University of California, Riverside, Riverside, CA 92521, USA; Environmental Toxicology Graduate Program, University of California, Riverside, Riverside, CA 92502, USA. Electronic address: yinsheng@ucr.edu.
University of California, Riverside · US

Funding

Research Training in Environmental ToxicologyT32ES018827 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Yinsheng Wang · 2010 to 2026
$5.3M
Quantitative Adductomics Approaches for Assessing the Occurrence and Repair of DNA AdductsR01CA210072 · NCI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI WANG, YINSHENG · 2017 to 2021
$1.8M
NCI NIH HHS R01 CA210072NIEHS NIH HHS T32 ES018827
6 · The paper itself

Abstract

N

Indexed as

AdenosineAdenylate KinaseAntineoplastic Agents, HormonalApoptosisBreast NeoplasmsCell ProliferationDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticHEK293 CellsHumansMCF-7 CellsMethylationMethyltransferasesReactive Oxygen SpeciesRNA, MessengerAdenosineAdenylate KinaseAntineoplastic Agents, HormonalMethyltransferasesMETTL3 protein, humanN-methyladenosineReactive Oxygen SpeciesRNA, MessengerTamoxifen

Identifiers

PMID32956623
PMCPMC7704734
OpenAlexW3083086776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.